Cancer cell immune escape and tumor progression by exploitation of anti-inflammatory and pro-inflammatory responses

R Kim, M Emi, K Tanabe - Cancer biology & therapy, 2005 - Taylor & Francis
Apoptotic cells can be eliminated by phagocytosis, which is mediated by antigen-presenting
cells (APCs), such as macrophages and dendritic cells (DCs), through phosphatidylserine …

Regulators of apoptosis: suitable targets for immune therapy of cancer

MH Andersen, JC Becker, P Straten - Nature Reviews Drug Discovery, 2005 - nature.com
Harnessing the immune system in the battle against cancer has been the focus of
tremendous research efforts during the past two decades. Several means for achieving this …

The role of neurokinin‐1 receptor in the microenvironment of inflammation and cancer

M Rosso, M Munoz, M Berger - The Scientific World Journal, 2012 - Wiley Online Library
The recent years have witnessed an exponential increase in cancer research, leading to a
considerable investment in the field. However, with few exceptions, this effort has not yet …

Synthetic CpG oligodeoxynucleotides augment BAFF‐and APRIL‐mediated immunoglobulin secretion

N Katsenelson, S Kanswal, M Puig… - European journal of …, 2007 - Wiley Online Library
The B lymphocyte‐activating factor belonging to TNF superfamily (BAFF) acts on B
lymphocytes through BAFF receptor (BAFF‐R), the transmembrane activator, calcium …

Enhanced transcutaneous immunization via dissolving microneedle array loaded with liposome encapsulated antigen and adjuvant

L Guo, J Chen, Y Qiu, S Zhang, B Xu, Y Gao - International journal of …, 2013 - Elsevier
Transcutaneous immunization (TCI) with dissolving microneedle arrays (DMAs) is a
promising vaccine administration method. In this work, we developed a TCI device …

Nanomaterials-Involved Tumor-Associated Macrophages' Reprogramming for Antitumor Therapy

SL Li, HY Hou, X Chu, YY Zhu, YJ Zhang, MD Duan… - ACS …, 2024 - ACS Publications
Tumor-associated macrophages (TAMs) play pivotal roles in tumor development. As primary
contents of tumor environment (TME), TAMs secrete inflammation-related substances to …

TLR ligand–peptide conjugate vaccines: toward clinical application

GGP Zom, S Khan, DV Filippov, F Ossendorp - Advances in immunology, 2012 - Elsevier
Approaches to treat cancer with therapeutic vaccination have made significant progress. In
order to induce efficient antitumor immunity, a vaccine should target and activate antigen …

Immunization of flavivirus West Nile recombinant envelope domain III protein induced specific immune response and protection against West Nile virus infection

JHJ Chu, CCS Chiang, ML Ng - The Journal of Immunology, 2007 - journals.aai.org
The domain III of the West Nile virus (WNV) envelope glycoprotein (E) was shown to serve
as virus attachment domain to the cellular receptor, and neutralizing Abs have been mapped …

TLR9 is critical for glioma stem cell maintenance and targeting

A Herrmann, G Cherryholmes, A Schroeder, J Phallen… - Cancer research, 2014 - AACR
Understanding supports for cancer stem–like cells in malignant glioma may suggest
therapeutic strategies for their elimination. Here, we show that the Toll-like receptor TLR9 is …

Immunization to protect the US Armed Forces: heritage, current practice, and prospects

JD Grabenstein, PR Pittman, JT Greenwood… - Epidemiologic …, 2006 - academic.oup.com
Americans serving with the US Armed Forces need protection from the dangerous infections
that they can contract during training, based on occupation, during overseas deployment, or …