A novel combined adjuvant for nasal delivery elicits mucosal immunity to influenza in aging
H Asanuma, NB Zamri, S Sekine, Y Fukuyama… - Vaccine, 2012 - Elsevier
Since a combination of flt3 ligand plasmid (pFL) and CpG-oligodeoxynucleotides (ODN) 3
as a dendritic cell (DC)-targeting double mucosal adjuvant elicited ovalbumin-specific …
as a dendritic cell (DC)-targeting double mucosal adjuvant elicited ovalbumin-specific …
Co-stimulatory agonists as immunological adjuvants
TA Barr, J Carlring, AW Heath - Vaccine, 2006 - Elsevier
The considerable advances made in the fields of molecular biology, genomics, proteomics
and protein engineering have led to the identification of a vast range of potential vaccine …
and protein engineering have led to the identification of a vast range of potential vaccine …
Intranasal immunization with HRSV prefusion F protein and CpG adjuvant elicits robust protective effects in mice
H Ren, H Li, L Cao, Z Wang, Y Zhou, J Guo, Y Zhang… - Vaccine, 2022 - Elsevier
Human respiratory syncytial virus (HRSV) is a leading cause of lower respiratory tract
infections in elderly individuals and young children/infants and can cause bronchiolitis and …
infections in elderly individuals and young children/infants and can cause bronchiolitis and …
Efficacy, immunogenicity and stability of a novel intranasal nanoemulsion-adjuvanted influenza vaccine in a murine model
T Hamouda, A Chepurnov, N Mank, J Knowlton… - Human …, 2010 - Taylor & Francis
Mutations of influenza virus increase concerns of worldwide epidemics resulting from the
newly emergent strains. Current influenza vaccines are inefficient and require annual …
newly emergent strains. Current influenza vaccines are inefficient and require annual …
[HTML][HTML] Cationic liposomes containing soluble Leishmania antigens (SLA) plus CpG ODNs induce protection against murine model of leishmaniasis
Abstract Development of an effective vaccine against leishmaniasis is possible due to the
fact that individuals cured from cutaneous leishmaniasis (CL) are protected from further …
fact that individuals cured from cutaneous leishmaniasis (CL) are protected from further …
Immunostimulatory oligonucleotides inhibit colonic proinflammatory cytokine production in ulcerative colitis
D Rachmilewitz, F Karmeli, S Shteingart… - Inflammatory bowel …, 2006 - Wiley Online Library
Background: We previously showed that Toll‐like receptor‐9 (TLR‐9) ligands ameliorate
experimental colitis. In this study, we evaluated the effect of TLR‐9 ligands on the generation …
experimental colitis. In this study, we evaluated the effect of TLR‐9 ligands on the generation …
DNA vaccines in sheep: CTLA-4 mediated targeting and CpG motifs enhance immunogenicity in a DNA prime/protein boost strategy
NJ Kennedy, TW Spithill, J Tennent, PR Wood… - Vaccine, 2006 - Elsevier
DNA vaccines have proven to be an efficient means of inducing immune responses in small
laboratory animals; however, their efficacy in large out-bred animal models has been much …
laboratory animals; however, their efficacy in large out-bred animal models has been much …
A built-in CpG adjuvant in RSV F protein DNA vaccine drives a Th1 polarized and enhanced protective immune response
Human respiratory syncytial virus (RSV) is the most significant cause of acute lower
respiratory infection in children. However, there is no licensed vaccine available. Here, we …
respiratory infection in children. However, there is no licensed vaccine available. Here, we …
Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary …
J Todoroff, B Ucakar, M Inglese… - European Journal of …, 2013 - Elsevier
The current Bacille Calmette–Guérin vaccine provides variable protection against
tuberculosis and new vaccination approaches are urgently needed. Pulmonary vaccination …
tuberculosis and new vaccination approaches are urgently needed. Pulmonary vaccination …
Protection of mice against Brucella abortus 544 challenge by vaccination with recombinant OMP28 adjuvanted with CpG oligonucleotides
P Kaushik, DK Singh, SV Kumar, AK Tiwari… - Veterinary research …, 2010 - Springer
Brucella abortus, a gram negative, facultative intracellular pathogen causes brucellosis in
many animal species and humans. Although live, attenuated vaccines are available against …
many animal species and humans. Although live, attenuated vaccines are available against …