Inflammation is a complicated physiological process that results in a variety of disorders.
Several inflammatory mediators are produced during this process, which is responsible for …

Anthranilic acid and its analogues present a privileged profile as pharmacophores for the
rational development of pharmaceuticals deliberated for managing the pathophysiology and …

Abstract 'Indane′ and its analogues indene, 1‐indenone, and 1, 3‐indandione present an
attractive biological profile for the rational development of therapeutic molecules. The …

Contemporary drug discovery approaches rely on library synthesis coupled with
combinatorial methods and high-throughput screening to identify leads. However, due to the …

Despite vigorous efforts, the COVID‐19 pandemic continues to take a toll on the global
health. The contemporary therapeutic regime focused on the viral spike proteins, viral 3CL …

Majority of the representative drugs customarily interact with multiple targets manifesting
unintended side effects. In addition, drug resistance and over expression of the cellular …

Oxicam is a class of non-steroidal anti-inflammatory drugs (NSAIDs) that exhibits structural
similarities to the enolic acid of 4-hydroxy-1, 2-benzothiazine carboxamides. The oxicam …

An over‐expression of COX‐2 isoenzyme belonging to the Cyclooxygenase Enzyme Family
triggers the overproduction of pro‐inflammatory prostaglandins that instigate the …

Abstract Imidazo [1, 2-a] pyridine is a privileged scaffold in medicinal chemistry with a wide
range of biological activities. C3-functionalized derivatives of Imidazo [1, 2-a] pyridine …

Inflammation is a natural response of the organism to damage, injury or tissue lesions
caused by foreign matter, trauma, infection, immune reactions and tissue necrosis. As being …