La-related proteins (LARPs) share a La motif (LaM) followed by an RNA recognition motif
(RRM). Together these are termed the La-module that, in the prototypical nuclear La protein …

RNA modifications, which are introduced post-transcriptionally, have recently been assigned
pivotal roles in the regulation of spermatogenesis and embryonic development. However …

Box C/D small nucleolar RNAs (C/D snoRNAs) represent an ancient family of small non-
coding RNAs that are classically viewed as housekeeping guides for the 2′-O-methylation …

Abstract Small Cajal body-specific RNAs (scaRNAs) guide post-transcriptional modification
of spliceosomal RNA and, while commonly altered in cancer, have poorly defined roles in …

RNA-binding proteins (RBPs) are well-known to bind RNA via a set of RNA-binding domains
(RBDs) and determine the fate and function of their RNA targets; inversely, some RBPs, in …

Telomerase reverse transcriptase (TERT) and the noncoding telomerase RNA (TR) subunit
constitute the core of telomerase. Additional subunits are required for ribonucleoprotein …

Filtering of nonspecifically binding contaminant proteins from affinity purification mass
spectrometry (AP-MS) data is a well-established strategy to improve statistical confidence in …

Spliceosomal small nuclear RNAs (snRNAs) are modified by small Cajal body (CB)-specific
ribonucleoproteins (scaRNPs) to ensure snRNP biogenesis and pre-mRNA splicing …

Long non-coding RNAs can often fold into different conformations. Telomerase RNA, an
essential component of the telomerase ribonucleoprotein (RNP) enzyme, must fold into a …

Abstract pre-mRNA splicing is a critical feature of eukaryotic gene expression. Both cis-and
trans-splicing rely on accurately recognising splice site sequences by spliceosomal U …