Breast cancer mortality is primarily due to the occurrence of metastatic disease. We have
identified a novel potential therapeutic agent derived from an edible root of the plant …

Inhibitors of excessive superoxide () generation have been indicated to be more effective
antioxidants than radical scavengers because anion is one of the precursors of several …

As previously demonstrated, deguelin [(7aS, BaS)-13, 13a-dihydro-9, 10-dimethoxy-3, 3-
dimethyl-3H-bis [1] benzo-pyrano [3, 4-b: 6′, 5′-e] pyran-7 (7aH)-one mediates anti …

Context Biotransformation systems are profitable tools for structural modification of bioactive
natural compounds into valuable biologically active terpenoids. Objective This study …

Background Colorectal carcinoma is one of the major causes of morbidity and mortality in
the Western World. Novel therapeutic approaches are needed for colorectal carcinoma …

Opuntia ficus-indica L. Mill cladodes are considered to be a source of an abundance of
bioactive compounds. To identify a natural product that can be used in the chemoprevention …

In this study, we focused on the effects of a bitter melon (Momordica charantia) leaf extract
(BMLE) and a purified component, Kuguacin J (KuJ), on androgen-dependent LNCaP …

Purpose Experimental evidence indicates a strong connection between oxidative damage,
cancer, and aging. Epidemiological observations suggest that a diet rich in fruits and …

The effects of dietary administration of capsaicin and rotenone on 4-nitroquinoline 1-oxide (4-
NQO)-induced tongue tumorigenesis were investigated in male F344 rats. In pilot studies …

Emerging data indicate a link between genetic instability and up-regulation of
cyclooxygenase-2 (COX-2). To see if individuals at high risk of oral cancer are candidates …