Objective Evidence reveals that γ-aminobutyric acid (GABA) receptors are involved in the
development of methamphetamine (METH) dependence. The GABA receptor delta subunit …

The introduction of the genome-wide association study transformed schizophrenia genetics
research and has promoted a genome-wide mindset that has stimulated the development of …

Protein interacting with C kinase (PICK1) is well conserved throughout evolution and plays a
critical role in synaptic plasticity by regulating the trafficking and posttranslational …

Research into the biological processes that increase susceptibility to methamphetamine
dependence has been conducted primarily in Asian populations. Using a case–control …

AKT1 (also known as protein kinase B, α), a serine/threonine kinase of AKT family, has been
implicated in both schizophrenia and methamphetamine (Meth) use disorders. AKT1 or its …

An increasing number of evidence showed that genetic factors might contribute to drug
abuse vulnerability. Data from genetic scans in humans suggest that brain-derived …

Heroin and methylamphetamine (METH) are two addictive drugs that cause serious
problems for society. Dopamine receptor D4 (DRD4), a key receptor in the dopaminergic …

Rationale Methamphetamine (MA) addiction is a major public health issue in the USA, with a
poorly understood genetic component. We previously identified heterogeneous nuclear …

Methamphetamine has powerful stimulant and euphoric effects that are experienced as
rewarding and encourage use. Methamphetamine addiction is associated with debilitating …

Background Drugs are chemicals which can disrupt the nerve cell functions of the brain. The
present study aims to investigate the addiction related gene (OPRM1) in three types of …