Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease
Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …
How vascular smooth muscle cell phenotype switching contributes to vascular disease
G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
Vascular smooth muscle cells in atherosclerosis: time for a re-assessment
MOJ Grootaert, MR Bennett - Cardiovascular research, 2021 - academic.oup.com
Vascular smooth muscle cells (VSMCs) are key participants in both early and late-stage
atherosclerosis. VSMCs invade the early atherosclerotic lesion from the media, expanding …
atherosclerosis. VSMCs invade the early atherosclerotic lesion from the media, expanding …
Stem cell pluripotency genes Klf4 and Oct4 regulate complex SMC phenotypic changes critical in late-stage atherosclerotic lesion pathogenesis
Background: Rupture and erosion of advanced atherosclerotic lesions with a resultant
myocardial infarction or stroke are the leading worldwide cause of death. However, we have …
myocardial infarction or stroke are the leading worldwide cause of death. However, we have …
Randall's plaque and calcium oxalate stone formation: role for immunity and inflammation
SR Khan, BK Canales… - Nature Reviews …, 2021 - nature.com
Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …
present on kidney papillary surfaces. Similar to the plaques formed during vascular …
Vascular calcification—new insights into its mechanism
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …
depending on the site (s) involved within the vessel, is closely related to cardiovascular …
Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness
AL Durham, MY Speer, M Scatena… - Cardiovascular …, 2018 - academic.oup.com
Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …
atherosclerotic plaque rupture. Calcification has been determined to be an active process …
[HTML][HTML] Bone grafts and biomaterials substitutes for bone defect repair: A review
W Wang, KWK Yeung - Bioactive materials, 2017 - Elsevier
Bone grafts have been predominated used to treat bone defects, delayed union or non-
union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency …
union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency …
Kidney stones
SR Khan, MS Pearle, WG Robertson… - Nature reviews Disease …, 2016 - nature.com
Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or
attached to the renal papillae. They contain crystalline and organic components and are …
attached to the renal papillae. They contain crystalline and organic components and are …
Atherosclerosis in chronic kidney disease: more, less, or just different?
JM Valdivielso, D Rodríguez-Puyol… - … , and vascular biology, 2019 - Am Heart Assoc
Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …
mainly from cardiovascular causes. The association between CKD on hemodialysis and …