Chlorogenic acid, the ester of caffeic acid with quinic acid, is one of the most abundant
polyphenols in the human diet. The antioxidant and anticarcinogenic properties of …

Chemoprevention, a relatively new and promising strategy to prevent cancer, is defined as
the use of natural dietary compounds and/or synthetic substances to block, inhibit, reverse …

Electrophilic compounds are a newly recognized class of redox‐active neuroprotective
compounds with electron deficient, electrophilic carbon centers that react with specific …

Human exposures to environmental toxicants have been associated with etiology of many
diseases including inflammation, cancer, and cardiovascular and neurodegenerative …

Epidemiologic studies have found an inverse association between consumption of tomato
products and the risk of certain types of cancers. However, the mechanisms underlying this …

Neurodegenerative diseases are normally distinguished as disorders with loss of neurons.
Various compounds are being tested to treat neurodegenerative diseases (NDs) but they …

Epithelial-mesenchymal transition (EMT) is a cellular process by which epithelial cells
transform to acquire mesenchymal phenotypes. Accumulating evidence indicate the …

Lycium barbarum polysaccharides (LBP), extracts from the wolfberries, are protective to
retina after ischemia-reperfusion (I/R). The antioxidant response element (ARE)–mediated …

Lung injury, which is associated with systemic inflammatory responses, is a common
problem with significant morbidity and mortality. Here, we examined the involvement of toll …

Nuclear factor-erythroid 2 p45 (NF-E2 p45)-related factor 2 (Nrf2) is a master regulator of
redox homoeostasis that allows cells to adapt to oxidative stress and also promotes cell …