Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment

MS Nadeem, I Kazmi, I Ullah, K Muhammad, F Anwar - Antioxidants, 2021 - mdpi.com
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

Pharmacological inhibition of ferroptosis as a therapeutic target for neurodegenerative diseases and strokes

Y Wang, S Wu, Q Li, H Sun, H Wang - Advanced Science, 2023 - Wiley Online Library
Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

Therapeutic potential of allicin and aged garlic extract in Alzheimer's disease

P Tedeschi, M Nigro, A Travagli, M Catani… - International Journal of …, 2022 - mdpi.com
Garlic, Allium sativum, has long been utilized for a number of medicinal purposes around the
world, and its medical benefits have been well documented. The health benefits of garlic …

Does inflammation play a major role in the pathogenesis of Alzheimer's disease?

B Wiatrak, P Jawień, A Szeląg… - NeuroMolecular …, 2023 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease leading to dementia for which no
effective medicine exists. Currently, the goal of therapy is only to slow down the inevitable …

Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

Neuroprotective efficacy of the bacterial metabolite, prodigiosin, against aluminium chloride‐induced neurochemical alternations associated with Alzheimer's disease …

KF Alsharif, A Albrakati, NE Al Omairi… - Environmental …, 2023 - Wiley Online Library
Prodigiosin (PDG) is a bacterial metabolite with numerous biological and pharmaceutical
properties. Exposure to aluminium is considered a root etiological factor in the pathological …

Are high copper levels related to Alzheimer's and Parkinson's diseases? A systematic review and meta-analysis of articles published between 2011 and 2022

F Scolari Grotto, V Glaser - Biometals, 2024 - Springer
Copper performs an important role in the brain, but in high levels it can be neurotoxic.
Further, some authors have described that copper dyshomeostasis could be related with …

[HTML][HTML] Effect and mechanism of acupuncture on Alzheimer's disease: a review

L Wu, Y Dong, C Zhu, Y Chen - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
This paper summarizes the experimental studies on acupuncture and moxibustion in the
treatment of Alzheimer's disease (AD) in recent years and expounds on the related indexes …

Garden Cress (Lepidium sativum) Seeds Ameliorated Aluminum-Induced Alzheimer Disease in Rats Through Antioxidant, Anti-Inflammatory, and Antiapoptotic …

MJ Balgoon - Neuropsychiatric Disease and Treatment, 2023 - Taylor & Francis
Background Bioaccumulation of aluminum in the brain is associated with adverse
neuroinflammatory and neurodegenerative changes, such as those seen in Alzheimer's …

[HTML][HTML] Novel insights into the immune cell landscape and gene signatures in autism spectrum disorder by bioinformatics and clinical analysis

H Li, Y Xu, W Li, L Zhang, X Zhang, B Li… - Frontiers in …, 2023 - frontiersin.org
The pathogenesis of autism spectrum disorder (ASD) is not well understood, especially in
terms of immunity and inflammation, and there are currently no early diagnostic or treatment …