Obesity and dyslipidemia: a review of current evidence

J Vekic, A Stefanovic, A Zeljkovic - Current Obesity Reports, 2023 - Springer
Abstract Purpose of Review Obesity is accompanied by atherogenic dyslipidemia, a specific
lipid disorder characterized by both quantitative and qualitative changes of plasma …

[HTML][HTML] Mechanisms of maternal diet-induced obesity affecting the offspring brain and development of affective disorders

DE Radford-Smith, DC Anthony - Metabolites, 2023 - mdpi.com
Depression and metabolic disease are common disorders that share a bidirectional
relationship and continue to increase in prevalence. Maternal diet and maternal behaviour …

[HTML][HTML] Vitamin D supplementation improves mitochondrial function and reduces inflammation in placentae of obese women

EA Phillips, N Hendricks, M Bucher… - Frontiers in …, 2022 - frontiersin.org
Background About 30% of women entering pregnancy in the US are obese. We have
previously reported mitochondrial dysregulation and increased inflammation in the …

Early life programming of health and disease: The long‐term consequences of obesity in pregnancy

SC Langley‐Evans - Journal of Human Nutrition and Dietetics, 2022 - Wiley Online Library
The prevalence of overweight and obesity is rising in all parts of the world and, among
young women, it presents a very clear danger during pregnancy. Women who are …

Metabolic abnormalities in the bone marrow cells of young offspring born to mothers with obesity

EA Phillips, YJ Alharithi, L Kadam… - International Journal of …, 2024 - nature.com
Abstract Background/Objectives Intrauterine metabolic reprogramming occurs in mothers
with obesity during gestation, putting the offspring at high risk of developing obesity and …

Maternal high-fat diet increases airway sensory innervation and reflex bronchoconstriction in adult offspring

GN Calco, YJ Alharithi, KR Williams… - … of Physiology-Lung …, 2023 - journals.physiology.org
Children born to obese mothers are prone to develop asthma and airway
hyperresponsiveness, but the mechanisms behind this are unclear. Here we developed a …

[HTML][HTML] Maternal high-fat diet impairs placental fatty acid β-oxidation and metabolic homeostasis in the offspring

L Zhang, Z Wang, H Wu, Y Gao, J Zheng… - Frontiers in Nutrition, 2022 - frontiersin.org
Maternal overnutrition can affect fetal growth and development, thus increasing susceptibility
to obesity and diabetes in later life of the offspring. Placenta is the central organ connecting …

Maternal-placental axis and its impact on fetal outcomes, metabolism, and development

B de Souza Lima, APV Sanches, MS Ferreira… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Maternal obesity could impact offspring's health. During “critical period” such as pregnancy
insults have a significant role in developing chronic diseases later in life. Literature has …

Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers

KRC Montaniel, M Bucher, EA Phillips, C Li… - … origins of health and …, 2022 - cambridge.org
Maternal obesity programs the offspring to metabolic diseases later in life; however, the
mechanisms of programming are yet unclear, and no strategies exist for addressing its …

[HTML][HTML] Increasing maternal age associates with lower placental CPT1B mRNA expression and acylcarnitines, particularly in overweight women

HEJ Yong, OC Watkins, TKL Mah… - Frontiers in …, 2023 - frontiersin.org
Older pregnant women have increased risks of complications including gestational diabetes
and stillbirth. Carnitine palmitoyl transferase (CPT) expression declines with age in several …