[HTML][HTML] Network pharmacology- and molecular docking-based analyses of the antihypertensive mechanism of Ilex kudingcha

F Liao, M Yousif, R Huang, Y Qiao, Y Hu - Frontiers in Endocrinology, 2023 - frontiersin.org
Herein, network pharmacology was used to identify the active components in Ilex kudingcha
and common hypertension-related targets. Gene Ontology (GO) and Kyoto Encyclopedia of …

Tou Nong powder obstructs ulcerative colitis through the regulation of NF-κB/NLRP3/Caspase-1/GSDMD inflammasome pyroptotic pathway

Z Ye, L Li, Y Li, Y Hu, M Wu, H Yu, Q Zhao… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Tou Nong Powder (TNP), a classical Chinese
medicinal formula originated from the Chinese Ming Dynasty, has been applied to treat skin …

[HTML][HTML] Multi-level advances in databases related to systems pharmacology in traditional Chinese medicine: a 60-year review

M Fan, C Jin, D Li, Y Deng, L Yao, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The therapeutic effects of traditional Chinese medicine (TCM) involve intricate interactions
among multiple components and targets. Currently, computational approaches play a pivotal …

[HTML][HTML] Uncovering the active constituents and mechanisms of Rujin Jiedu powder for ameliorating LPS-induced acute lung injury using network pharmacology and …

Y Ma, H Xu, G Chen, W Liu, C Ma, J Meng… - Frontiers in …, 2023 - frontiersin.org
Background: Acute lung injury (ALI) is a common clinical disease with high mortality. Rujin
Jiedu powder (RJJD) has been clinically utilized for the treatment of ALI in China, but the …

[HTML][HTML] Exploring the inhibition mechanism of interleukin-1-beta in gouty arthritis by polygonum cuspidatum using network pharmacology and molecular docking: A …

X Ge, Y Zhang, R Fang, J Zhao, J Huang - Medicine, 2023 - journals.lww.com
Polygonum cuspidatum (Huzhang, HZ) is one of the commonly used traditional Chinese
medicines for treating gouty arthritis (GA), but the specific mechanism is not clear. This study …

Chemical Composition and Antibacterial and Antiulcerative Colitis Activities of Essential Oil from Pruni Semen

YL Wang, DQ Lang, C Wu, QC Chen… - Journal of Agricultural …, 2024 - ACS Publications
This study was sought to investigate the chemical composition and antibacterial and
antiulcerative colitis (UC) effects of essential oil from Pruni Semen (PSEO). A GC-MS assay …

Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models

L Duan, Z Hao, R Ji, X Li, H Wang, Y Su, F Guan… - International Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disease with high prevalence,
long duration and poor prognosis. The blood-brain barrier (BBB) is a physiologic barrier in …

Exploring the molecular mechanism of the antioxidant activity of medicine and food homology licorice flavonoids based on pharmacophore theory and quantum …

Y Hu, P Liang, Z Wang, CP Jiang, Y Guo… - Journal of Food …, 2023 - Wiley Online Library
Licorice flavonoids are a kind of flavonoids extracted from the root of licorice, which have
good antioxidant activity and are widely used in the food industry. In the early research of the …

[HTML][HTML] Salvigenin suppresses hepatocellular carcinoma glycolysis and chemoresistance through inactivating the Pi3K/Akt/Gsk-3Β pathway

H Shao, J Chen, A Li, L Ma, Y Tang, H Chen… - Applied Biochemistry …, 2023 - Springer
Abstract Salvigenin is a Trimethoxylated Flavone enriched in Scutellariae Barbatae Herba
and Scutellariae Radix and is demonstrated to have anti-tumor properties in colon cancer …

Chaihu Shugan powder influences nonalcoholic fatty liver disease in rats in remodeling microRNAome and decreasing fatty acid synthesis

C Zheng, H Nie, M Pan, W Fan, D Pi, Z Liang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Chaihu Shugan powder (CSP) plays an important
role in the prevention and treatment of nonalcoholic fatty liver disease (NAFLD) through a …