[HTML][HTML] Novel SARS-CoV-2 variants: the pandemics within the pandemic
Background Many new variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …
[HTML][HTML] Emerging SARS-CoV-2 variants of concern and potential intervention approaches
J Khateeb, Y Li, H Zhang - Critical Care, 2021 - Springer
The major variant of concerns (VOCs) have shared mutations in severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) spike proteins, mostly on the S1 unit and resulted in …
syndrome coronavirus 2 (SARS-CoV-2) spike proteins, mostly on the S1 unit and resulted in …
[HTML][HTML] Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2
Abstract The B. 1.1. 529/Omicron variant of SARS-CoV-2 was only recently detected in
southern Africa, but its subsequent spread has been extensive, both regionally and globally …
southern Africa, but its subsequent spread has been extensive, both regionally and globally …
[HTML][HTML] SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape,–, have activity
against diverse sarbecoviruses,,–, and be highly protective through viral neutralization,,–and …
against diverse sarbecoviruses,,–, and be highly protective through viral neutralization,,–and …
[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)
A Aleem, AS Ab, AK Slenker - 2021 - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …
COVID-19. Outline the latest treatments available in the management of COVID-19 …
[HTML][HTML] Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals
The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …
[HTML][HTML] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity
C Motozono, M Toyoda, J Zahradnik, A Saito… - Cell host & …, 2021 - cell.com
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …
mutations can affect viral properties such as infectivity and immune resistance. Although the …
SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern
A novel variant of concern (VOC) named CAL. 20C (B. 1.427/B. 1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …
[HTML][HTML] Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …
[HTML][HTML] Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis
for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute …
for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute …