Portrait of a killer: Uncovering resistance mechanisms and global spread of Acinetobacter baumannii

AK Cain, M Hamidian - PLoS Pathogens, 2023 - journals.plos.org
Antibiotic resistance is a growing global concern in the field of medicine as it renders
bacterial infections difficult to treat and often more severe. Acinetobacter baumannii is a …

IS26 and the IS26 family: versatile resistance gene movers and genome reorganizers

CJ Harmer, RM Hall - Microbiology and Molecular Biology …, 2024 - Am Soc Microbiol
In Gram-negative bacteria, the insertion sequence IS 26 is highly active in disseminating
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …

Interbacterial transfer of carbapenem resistance and large antibiotic resistance islands by natural transformation in pathogenic Acinetobacter

AS Godeux, E Svedholm, S Barreto, A Potron… - MBio, 2022 - Am Soc Microbiol
Acinetobacter baumannii infection poses a major health threat, with recurrent treatment
failure due to antibiotic resistance, notably to carbapenems. While genomic analyses of …

Accessory genomic epidemiology of cocirculating Acinetobacter baumannii clones

V Mateo-Estrada, JL Fernández-Vázquez… - …, 2021 - Am Soc Microbiol
Acinetobacter baumannii has become one of the most important multidrug-resistant
nosocomial pathogens all over the world. Nonetheless, very little is known about the …

Genetic Configuration of Genomic Resistance Islands in Acinetobacter baumannii Clinical Isolates From Egypt

SM Hamed, AFA Hussein, MH Al-Agamy… - Frontiers in …, 2022 - frontiersin.org
In Acinetobacter baumannii (A. baumannii), a wide repertoire of resistance genes is often
carried within genomic resistance islands (RIs), particularly in high-risk global clones (GCs) …

Genomic analysis of CTX-M-115 and OXA-23/-72 co-producing Acinetobacter baumannii, and their potential to spread resistance genes by natural transformation

JB Vuillemenot, M Bour, R Beyrouthy… - Journal of …, 2022 - academic.oup.com
Abstract Objectives To characterize Acinetobacter baumannii strains co-producing the ESBL
CTX-M-115 and carbapenem-hydrolysing class D β-lactamases (CHDLs), and to assess the …

[HTML][HTML] The extensively antibiotic resistant ST111 Acinetobacter baumannii isolate RBH2 carries an extensive mobile element complement of plasmids, transposons …

SJ Ambrose, M Hamidian, RM Hall - Plasmid, 2023 - Elsevier
The complete genome of RBH2, a sporadic, carbapenem resistant ST111 Acinetobacter
baumannii isolate from Brisbane, Australia was determined and analysed. RBH2 is …

Dissemination of novel Tn7 family transposons carrying genes for synthesis and uptake of fimsbactin siderophores among Acinetobacter baumannii isolates

M Hamidian, RM Hall - Microbial genomics, 2021 - microbiologyresearch.org
Acinetobacter baumannii is a successful opportunistic pathogen that can compete for iron
under iron-limiting conditions. Here, large novel transposons that carry genes for synthesis …

OXA-48-like carbapenemases in Proteus mirabilis - novel genetic environments and a challenge for detection

J Sattler, J Noster, Y Stelzer, M Spille… - Emerging Microbes & …, 2024 - Taylor & Francis
OXA-48-like enzymes represent the most frequently detected carbapenemases in
Enterobacterales in Western Europe, North Africa and the Middle East. In contrast to other …

Occurrence of Acinetobacter baumannii genomic resistance islands (AbGRIs) in Acinetobacter baumannii strains belonging to global clone 2 obtained from COVID …

G Naderi, M Asadian, PA Khaki, M Salehi, A Abdollahi… - BMC microbiology, 2023 - Springer
Abstract Aim The Acinetobacter baumannii genomic resistance islands (AbGRIs), which
were characterized in the genome of the global clone 2 (GC2) A. baumannii contain …