[HTML][HTML] Natural small molecules in breast cancer treatment: understandings from a therapeutic viewpoint

MR Islam, F Islam, MH Nafady, M Akter, S Mitra, R Das… - Molecules, 2022 - mdpi.com
Breast cancer (BrCa) is the most common malignancy in women and the second most
significant cause of death from cancer. BrCa is one of the most challenging malignancies to …

[HTML][HTML] From plantation to cup: Changes in bioactive compounds during coffee processing

F Bastian, OS Hutabarat, A Dirpan, F Nainu, H Harapan… - Foods, 2021 - mdpi.com
Coffee is consumed not just for its flavor, but also for its health advantages. The quality of
coffee beverages is affected by a number of elements and a series of processes, including …

Allium cepa: A Treasure of Bioactive Phytochemicals with Prospective Health Benefits

AJ Chakraborty, TM Uddin… - Evidence‐Based …, 2022 - Wiley Online Library
As Allium cepa is one of the most important condiment plants grown and consumed all over
the world, various therapeutic and pharmacological effects of A. cepa were reviewed. Onion …

[HTML][HTML] The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Pharmacological features, health benefits and clinical implications of honokiol

F Khatoon, S Ali, V Kumar, AM Elasbali… - Journal of …, 2023 - Taylor & Francis
Honokiol (HNK) is a natural polyphenolic compound extracted from the bark and leaves of
Magnolia grandiflora. It has been traditionally used as a medicinal compound to treat …

[HTML][HTML] A novel combination therapy with Cabozantinib and Honokiol effectively inhibits c-Met-Nrf2-induced renal tumor growth through increased oxidative stress

L Rawat, M Balan, Y Sasamoto, A Sabarwal, S Pal - Redox biology, 2023 - Elsevier
Receptor tyrosine kinase (RTK), c-Met, is overexpressed and hyper active in renal cell
carcinoma (RCC). Most of the therapeutic agents mediate cancer cell death through …

Novel insights on ferroptosis modulation as potential strategy for cancer treatment: when nature kills

V Consoli, AN Fallica, V Sorrenti, V Pittala… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: The multifactorial nature of the mechanisms implicated in cancer development
still represents a major issue for the success of established antitumor therapies. The …

[HTML][HTML] Targeting cell signaling pathways in lung cancer by bioactive phytocompounds

N Choudhary, S Bawari, JT Burcher, D Sinha, D Tewari… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is the leading cause of mortality in cancer patients, causing
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …

Honokiol@ PF127 crosslinked hyaluronate-based hydrogel for promoting wound healing by regulating macrophage polarization

Q Wei, Z Jin, W Zhang, Y Zhao, Y Wang, Y Wei… - Carbohydrate …, 2023 - Elsevier
Bacterial infection, oxidative stress and inflammation are the main obstacles in wound
healing. Hydrogels with moist and inherent properties are beneficial to wound healing. Here …

Honokiol attenuates high glucose‐induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC‐1α pathway in Schwann cells

M Hu, W Jiang, C Ye, T Hu, Q Yu, M Meng… - Phytotherapy …, 2023 - Wiley Online Library
Schwann cells injury induced by high glucose (HG) contributes to the development of
diabetic peripheral neuropathy (DPN). Honokiol has been reported to regulate glucose …