Rheumatoid arthritis (RA) is a common, chronic, systemic autoimmune disease, and its
clinical features are the proliferation of joint synovial tissue, the formation of pannus and the …

Aims: In this article, inflammatory mechanisms that link periodontal diseases to
cardiovascular diseases are reviewed. Methods: This article is a literature review. Results …

Natural Abs, belonging to isotypes IgM, IgG3, and IgA, were discovered nearly half a century
ago. Despite knowledge about the role of the polyreactive natural IgM in pathogen …

The existence of IgM has been known for more than a century, but its importance in immunity
and autoimmunity continues to emerge. Studies of mice deficient in secreted IgM have …

Antibodies are a vital part of the armamentarium of the adaptive immune system for the fine-
tuning of the recognition and response to foreign threats. However, in health there are some …

Oxidative modification of LDL is known to elicit an array of pro-atherogenic responses, but it
is generally underappreciated that oxidized LDL (OxLDL) exists in multiple forms …

Natural killer T (NKT) cells constitute a highly conserved T lymphocyte subpopulation that
has the potential to regulate many types of immune responses through the rapid secretion of …

Elevated levels of cholesteryl ester (CE)–enriched apoB containing plasma lipoproteins lead
to increased foam cell formation, the first step in the development of atherosclerosis …

Studying the phenomenon of cellular senescence has been hindered by the lack of
senescence-specific markers. As such, detection of proteins informally associated with …

B‐1 cells play critical roles in defending against microbial invasion and in housekeeping
removal of cellular debris. B‐1 cells secrete natural antibody and manifest functions that …