Adolescent acne vulgaris: current and emerging treatments

AM Layton, J Ravenscroft - The Lancet Child & Adolescent Health, 2023 - thelancet.com
Acne vulgaris is one of the commonest inflammatory skin diseases seen worldwide, affecting
all ethnicities and races, with a peak prevalence between age 15 years and 20 years. The …

Role of sebaceous glands in inflammatory dermatoses

VY Shi, M Leo, L Hassoun, DS Chahal… - Journal of the American …, 2015 - Elsevier
Skin is an important interface between the host and its environment. Inflammatory
dermatoses often have disrupted skin barrier function, rendering patients more susceptible …

Evaluation of the clinical efficacy of fractional radiofrequency microneedle treatment in acne scars and large facial pores

SI Cho, BY Chung, MG Choi, JH Baek… - Dermatologic …, 2012 - journals.lww.com
Background Fractional technology overcomes the problems of ablative lasers, such as
inaccurate depth control and damage to the epidermis. Minimally invasive fractional …

Comparison of fractional microneedling radiofrequency and bipolar radiofrequency on acne and acne scar and investigation of mechanism: comparative randomized …

S Min, SY Park, JY Yoon, DH Suh - Archives of dermatological research, 2015 - Springer
Fractional microneedling radiofrequency (FMR) is one of the promising methods in acne
treatment. Moreover, bipolar radiofrequency (BR) generates heat thereby which induces …

[PDF][PDF] Current concepts in acne pathogenesis: pathways to inflammation

JKL Tan, LF Stein Gold, AF Alexis… - Semin Cutan Med …, 2018 - scmsjournal.com
■ Abstract Acne is a disease of pilosebaceous inflammation. Pivotal in pathogenesis are
the roles of hormones (insulin, insulinlike growth factor-1, androgens), Propionibacterium …

Gelatin-based dissolvable antibacterial films reinforced with metallic nanoparticles

S Shankar, L Jaiswal, PR Selvakannan, KS Ham… - RSC …, 2016 - pubs.rsc.org
Six different types of metallic and bimetallic nanoparticles (Au, Ag, Cu, AuAg, AuCu, and
AgCu) were prepared using an aqueous extract of Artemisia scoparia (AS) as reducing and …

Opportunities and challenges in developing stearoyl-coenzyme A desaturase-1 inhibitors as novel therapeutics for human disease: miniperspective

Z Zhang, NA Dales, MD Winther - Journal of medicinal chemistry, 2014 - ACS Publications
This review provides an overview of stearoyl-coenzyme A desaturase-1 (SCD1) as a novel
therapeutic target for metabolic disorders and other indications. Target validation is …

Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition

WP Esler, GJ Tesz, MK Hellerstein, C Beysen… - Science Translational …, 2019 - science.org
Sebum plays important physiological roles in human skin. Excess sebum production
contributes to the pathogenesis of acne vulgaris, and suppression of sebum production …

Treatment of acne vulgaris with fractional radiofrequency microneedling

ST Kim, KH Lee, HJ Sim, KS Suh… - The Journal of …, 2014 - Wiley Online Library
Fractional radiofrequency microneedling is a novel radiofrequency technique that uses
insulated microneedles to deliver energy to the deep dermis at the point of penetration …

Effect of Evening Primrose Oil Supplementation on Selected Parameters of Skin Condition in a Group of Patients Treated with Isotretinoin—A Randomized Double …

A Kaźmierska, I Bolesławska, A Polańska… - Nutrients, 2022 - mdpi.com
Background: Retinoids, which include isotretinoin, reduce sebum levels, the degree of
epidermal wetness (CORN) and cause an increase in transepidermal water loss (TEWL) …