An appraisal of anticancer activity with structure–activity relationship of quinazoline and quinazolinone analogues through EGFR and VEGFR inhibition: A review

K Haider, S Das, A Joseph… - Drug Development …, 2022 - Wiley Online Library
Cancer is one of the leading causes of death. Globally a huge number of deaths and new
incidences are reported annually. Heterocyclic compounds have been proved to be very …

LncRNAs LCETRL3 and LCETRL4 at chromosome 4q12 diminish EGFR-TKIs efficiency in NSCLC through stabilizing TDP43 and EIF2S1

Y Li, Y Shen, M Xie, B Wang, T Wang, J Zeng… - … and Targeted Therapy, 2022 - nature.com
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are effective
targeted therapy drugs for advanced non-small cell lung cancer (NSCLC) patients carrying …

Targeting the epidermal growth factor receptor in EGFR-mutated lung cancer: current and emerging therapies

K Khaddour, S Jonna, A Deneka, JD Patel… - Cancers, 2021 - mdpi.com
Simple Summary Epidermal growth factor receptor (EGFR) mutations occur in a significant
number of lung cancer patients. Treatment outcomes in this subset of patients has greatly …

Current treatment strategies for EGFR-mutated non-small cell lung cancer: from first line to beyond osimertinib resistance

T Araki, S Kanda, H Horinouchi… - Japanese Journal of …, 2023 - academic.oup.com
Osimertinib, a third-generation EGFR TKI, is the standard therapy for previously untreated
EGFR-mutated non-small cell lung cancer patients following the landmark FLAURA study …

Potential applications of nanoparticles in improving the outcome of lung cancer treatment

A Girigoswami, K Girigoswami - Genes, 2023 - mdpi.com
Lung cancer is managed using conventional therapies, including chemotherapy, radiation
therapy, or a combination of both. Each of these therapies has its own limitations, such as …

Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC)

C O'Leary, H Gasper, KB Sahin, M Tang, A Kulasinghe… - Pharmaceuticals, 2020 - mdpi.com
Epidermal growth factor receptor (EGFR) mutations are the most common oncogenic drivers
in non-small-cell lung cancer (NSCLC). Significant developments have taken place which …

Treatment Strategies for Non-Small Cell Lung Cancer with Common EGFR Mutations: A Review of the History of EGFR TKIs Approval and Emerging Data

JA Marin-Acevedo, B Pellini, EMO Kimbrough, JK Hicks… - Cancers, 2023 - mdpi.com
Simple Summary The management of non-small cell lung cancer with a common EGFR
mutation has evolved over the past decades. While frontline use of second-or third …

Therapy for stage IV non–small cell lung cancer with driver alterations: ASCO living guideline, version 2023.3

IA Jaiyesimi, NB Leighl, N Ismaila, K Alluri… - Journal of clinical …, 2024 - ascopubs.org
Living guidelines are developed for selected topic areas with rapidly evolving evidence that
drives frequent change in recommended clinical practice. Living guidelines are updated on …

[HTML][HTML] Epidermal growth factor receptors siRNA-conjugated collagen modified gold nanoparticles for targeted imaging and therapy of lung cancer

AYH Yu, RH Fu, S Hsu, CF Chiu, WH Fang… - Materials Today …, 2021 - Elsevier
Epidermal growth factor receptor (EGFR), a critical factor promotes lung cancer cell
proliferation and survival. Knockdown of EGFR expression thus promise beating lung cancer …

CT-based radiomics signatures can predict the tumor response of non-small cell lung cancer patients treated with first-line chemotherapy and targeted therapy

F Yang, J Zhang, L Zhou, W Xia, R Zhang, H Wei… - European …, 2022 - Springer
Objectives The goal of this study was to evaluate the effectiveness of radiomics signatures
on pre-treatment computed tomography (CT) images of lungs to predict the tumor responses …