Putting the spotlight back on plant suspension cultures
Plant cell suspension cultures have several advantages that make them suitable for the
production of recombinant proteins. They can be cultivated under aseptic conditions using …
production of recombinant proteins. They can be cultivated under aseptic conditions using …
Large‐scale production of pharmaceutical proteins in plant cell culture—the protalix experience
Y Tekoah, A Shulman, T Kizhner… - Plant biotechnology …, 2015 - Wiley Online Library
Protalix Biotherapeutics develops recombinant human proteins and produces them in plant
cell culture. Taliglucerase alfa has been the first biotherapeutic expressed in plant cells to be …
cell culture. Taliglucerase alfa has been the first biotherapeutic expressed in plant cells to be …
Engineering considerations on extrusion-based bioprinting: interactions of material behavior, mechanical forces and cells in the printing needle
Systematic analysis of the extrusion process in 3D bioprinting is mandatory for process
optimization concerning production speed, shape fidelity of the 3D construct and cell …
optimization concerning production speed, shape fidelity of the 3D construct and cell …
Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures
“Molecular farming” in plants with significant advantages in cost and safety is touted as a
promising platform for the production of complex pharmaceutical proteins. While whole-plant …
promising platform for the production of complex pharmaceutical proteins. While whole-plant …
Bioprocessing of plant cell cultures for mass production of targeted compounds
MI Georgiev, J Weber, A Maciuk - Applied microbiology and biotechnology, 2009 - Springer
More than a century has passed since the first attempt to cultivate plant cells in vitro. During
this time, plant cell cultures have become increasingly attractive and cost-effective …
this time, plant cell cultures have become increasingly attractive and cost-effective …
Biochemical engineering of the production of plant-specific secondary metabolites by cell suspension cultures
JJ Zhong - Plant cells, 2001 - Springer
Plant cell culture has recently received much attention as a useful technology for the
production of valuable plant-derived secondary metabolites such as paclitaxel and ginseng …
production of valuable plant-derived secondary metabolites such as paclitaxel and ginseng …
Bioreactor systems for in vitro production of foreign proteins using plant cell cultures
TK Huang, KA McDonald - Biotechnology advances, 2012 - Elsevier
Plant cells have been demonstrated to be an attractive heterologous expression host (using
whole plants and in vitro plant cell cultures) for foreign protein production in the past …
whole plants and in vitro plant cell cultures) for foreign protein production in the past …
Bioreactor engineering for recombinant protein production in plant cell suspension cultures
TK Huang, KA McDonald - Biochemical Engineering Journal, 2009 - Elsevier
A review of over 15 years of research, development and commercialization of plant cell
suspension culture as a bioproduction platform is presented. Plant cell suspension culture …
suspension culture as a bioproduction platform is presented. Plant cell suspension culture …
Plant cell culture for production of paclitaxel and other taxanes
JJ Zhong - Journal of bioscience and bioengineering, 2002 - Elsevier
Great advances in cell cultures of Taxus spp. for production of Taxol™(generic name:
paclitaxel) and other taxanes (taxoids) have been achieved in the past decade. This article …
paclitaxel) and other taxanes (taxoids) have been achieved in the past decade. This article …
Think outside the box: 3D bioprinting concepts for biotechnological applications–recent developments and future perspectives
F Krujatz, S Dani, J Windisch, J Emmermacher… - Biotechnology …, 2022 - Elsevier
Abstract 3D bioprinting–the fabrication of geometrically complex 3D structures from
biocompatible materials containing living cells using additive manufacturing technologies–is …
biocompatible materials containing living cells using additive manufacturing technologies–is …