In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When
the balance is broken toward an overabundance of ROS, oxidative stress appears and may …

With extended periods of time following ovulation, the metaphase II stage oocyte
experiences deterioration in quality referred to as post-ovulatory oocyte ageing. Post …

Abstract STUDY QUESTION Is SIRT1 involved in the oxidative stress (OS) response in
mouse oocytes? SUMMARY ANSWER SIRT1 plays a pivotal role in the adaptive response …

The quality of metaphase II oocytes deteriorates rapidly following ovulation as the result of
an aging process associated with impaired fertilizing potential, disrupted developmental …

Objective To study follicular microenvironment in terms of free radical dynamics, oocyte
quality, and assisted reproductive technology (ART) outcomes among women with (group A) …

Abstract STUDY QUESTION Are phospholipase C zeta 1 (PLCZ1) mutations associated with
fertilization failure (FF) after ICSI? SUMMARY ANSWER New mutations in the PLCZ1 …

Calcium (Ca2+) signals initiate egg activation across the animal kingdom and in at least
some plants. These signals are crucial for the success of development and, in the case of …

Calcium (Ca++) is one of the major signal molecules that regulate various aspects of cell
functions including cell cycle progression, arrest, and apoptosis in wide variety of cells. This …

Background Oocytes may undergo two types of aging. The first is induced by exposure to an
aged ovarian microenvironment before being ovulated, known as 'reproductive or maternal …

Simple Summary In vitro embryo production (IVEP) is a technology that is widely used in the
field of reproductive biology. The first and most important step of IVEP is termed in vitro …