Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

The chemistry of organic contrast agents in the NIR‐II window

J Mu, M Xiao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H Xiong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

Activatable molecular probes for fluorescence-guided surgery, endoscopy and tissue biopsy

Y Zhang, G Zhang, Z Zeng, K Pu - Chemical Society Reviews, 2022 - pubs.rsc.org
The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance

A Ji, H Lou, C Qu, W Lu, Y Hao, J Li, Y Wu… - nature …, 2022 - nature.com
It is highly important and challenging to develop donor-acceptor-donor structured small-
molecule second near-infrared window (NIR-II) dyes with excellent properties such as water …

Controlled sequential in situ self-assembly and disassembly of a fluorogenic cisplatin prodrug for cancer theranostics

X Wen, R Zhang, Y Hu, L Wu, H Bai, D Song… - Nature …, 2023 - nature.com
Temporal control of delivery and release of drugs in tumors are important in improving
therapeutic outcomes to patients. Here, we report a sequential stimuli-triggered in situ self …

A dual‐locked activatable phototheranostic probe for biomarker‐regulated photodynamic and photothermal cancer therapy

X Wei, C Zhang, S He, J Huang… - Angewandte Chemie …, 2022 - Wiley Online Library
Activatable phototheranostics holds promise for precision cancer treatment owing to the
“turn‐on” signals and therapeutic effects. However, most activatable phototheranostic …

Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …