The epidemiology and etiology of azoospermia

M Cocuzza, C Alvarenga, R Pagani - Clinics, 2013 - SciELO Brasil
The misconception that infertility is typically associated with the female is commonly faced in
the management of infertile men. It is uncommon for a patient to present for an infertility …

Male infertility and environmental exposure to lead and cadmium

S Benoff, A Jacob, IR Hurley - Human reproduction update, 2000 - academic.oup.com
Humans are exposed occupationally and environmentally to metal aerosols including lead
(Pb2+) and cadmium (Cd2+). These toxicants accumulate in male reproductive organs …

Recommendations for the classification of diseases as CFTR-related disorders

C Bombieri, M Claustres, K De Boeck, N Derichs… - Journal of Cystic …, 2011 - Elsevier
Several diseases have been clinically or genetically related to cystic fibrosis (CF), but a
consensus definition is lacking. Here, we present a proposal for consensus guidelines on …

Genetic risk factors in infertile men with severe oligozoospermia and azoospermia

GR Dohle, DJJ Halley, JO Van Hemel… - Human …, 2002 - academic.oup.com
BACKGROUND: Male infertility due to severe oligozoospermia and azoospermia has been
associated with a number of genetic risk factors. METHODS: In this study 150 men from …

Fertilization and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men

GD Palermo, PN Schlegel, JJ Hariprashad… - Human …, 1999 - academic.oup.com
The evident ability of the intracytoplasmic sperm injection (ICSI) procedure to achieve high
fertilization and pregnancy rates regardless of semen characteristics has induced its …

Distinct spectrum of CFTR gene mutations in congenital absence of vas deferens

T Dörk, B Dworniczak, C Aulehla-Scholz, D Wieczorek… - Human genetics, 1997 - Springer
Congenital absence of the vas deferens (CAVD) is a frequent cause for obstructive
azoospermia and accounts for 1%–2% of male infertility. A high incidence of mutations of the …

Assessing the disease-liability of mutations in CFTR

C Ferec, GR Cutting - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Over 1900 mutations have been reported in the cystic fibrosis transmembrane conductance
regulator (CFTR), the gene defective in patients with cystic fibrosis. These mutations have …

Severe male factor in in vitro fertilization: definition, prevalence, and treatment. An update

R Mazzilli, A Vaiarelli, L Dovere… - Asian Journal of …, 2022 - journals.lww.com
Abstract Infertility affects 10%–15% of couples worldwide. Of all infertility cases, 20%–70%
are due to male factors. In the past, men with severe male factor (SMF) were considered …

[HTML][HTML] CUA Guideline: The workup of azoospermic males

K Jarvi, K Lo, A Fischer, J Grantmyre, A Zini… - Canadian Urological …, 2010 - ncbi.nlm.nih.gov
A committee was established at the request of the CUA to determine guidelines for the
investigation and management of azoospermia. Members of the committee, all of whom …

Proportion of cystic fibrosis gene mutations not detected by routine testing in men with obstructive azoospermia

V Mak, J Zielenski, LC Tsui, P Durie, A Zini, S Martin… - Jama, 1999 - jamanetwork.com
ContextInfertile men with obstructive azoospermia may have mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) gene, many of which are rare in classic …