miRNA regulatory functions in farm animal diseases, and biomarker potentials for effective therapies

DN Do, PL Dudemaine, M Mathur… - International journal of …, 2021 - mdpi.com
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene expression post-
transcriptionally by targeting either the 3′ untranslated or coding regions of genes. They …

Host non-coding RNA regulates influenza A virus replication

Y Liao, S Guo, G Liu, Z Qiu, J Wang, D Yang, X Tian… - Viruses, 2021 - mdpi.com
Outbreaks of influenza, caused by the influenza A virus (IAV), occur almost every year in
various regions worldwide, seriously endangering human health. Studies have shown that …

Action mechanisms and characteristics of miRNAs to regulate virus replication

Y Zhu, G Zhang, X Zhou, H Shang, L Li, T Xu - Virology, 2023 - Elsevier
MicroRNAs (miRNAs) have the potential to be explored as antiviral products. It is known that
miRNAs have different kinds of target mRNAs and different target sites in mRNAs, and that …

Integrated analysis of microRNA-mRNA expression in A549 cells infected with influenza A viruses (IAVs) from different host species

J Gao, L Gao, R Li, Z Lai, Z Zhang, X Fan - Virus research, 2019 - Elsevier
Although several miRNAs have been demonstrated to be involved in the influenza virus
replication cycle, the identification of miRNAs and mRNAs that are expressed in A549 cells …

Animal models for influenza A virus infection incorporating the involvement of innate host defenses: enhanced translational value of the porcine model

SMR Starbæk, L Brogaard, HD Dawson, AD Smith… - ILAR …, 2018 - academic.oup.com
Influenza is a viral respiratory disease having a major impact on public health. Influenza A
virus (IAV) usually causes mild transitory disease in humans. However, in specific groups of …

[HTML][HTML] The influence of host miRNA binding to RNA within RNA viruses on virus multiplication

L Lei, A Cheng, M Wang, R Jia - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
microRNAs (miRNAs), non-coding RNAs about 22 nt long, regulate the post-transcription
expression of genes to influence many cellular processes. The expression of host miRNAs is …

Interplay between host non-coding RNAs and influenza viruses

G Bamunuarachchi, S Pushparaj, L Liu - RNA biology, 2021 - Taylor & Francis
Influenza virus infection through seasonal epidemics and occasional pandemics has been a
major public health concern for decades. Incomplete protection from vaccination and …

[HTML][HTML] Identification of a novel antiviral micro-RNA targeting the NS1 protein of the H1N1 pandemic human influenza virus and a corresponding viral escape …

L Bavagnoli, G Campanini, M Forte, G Ceccotti… - Antiviral Research, 2019 - Elsevier
The influenza A virus (IAV) NS1 protein is one of the major regulators of pathogenicity, being
able to suppress innate immune response and host protein synthesis. In this study we …

An atlas of expression quantitative trait loci of microRNAs in longissimus muscle of eight-way crossbred pigs

L Zhong, M Zheng, Y Huang, T Jiang, B Yang… - Journal of Genetics and …, 2023 - Elsevier
MicroRNAs (miRNAs) are key regulators of myocyte development and traits, yet insight into
the genetic basis of variation in miRNA expression is still limited. Here, we present a …

Synchronized orchestration of miR-99b and let-7g positively regulates rotavirus infection by modulating autophagy

U Mukhopadhyay, S Chanda, U Patra, A Mukherjee… - Scientific Reports, 2019 - nature.com
Rotavirus (RV), the major etiological agent of viral gastroenteritis in young children, kills over
200 thousand infants each year. In spite of available vaccines, rotaviral diarrhoea is still a …