Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of action
H Lee, S Yang, SH Shin - Journal of Analytical Science and Technology, 2023 - Springer
Amphipathic α-helical peptides (AHPs) have shown potential as a therapeutic approach
against multi-drug-resistant bacterial infections due to their broad-spectrum antimicrobial …
against multi-drug-resistant bacterial infections due to their broad-spectrum antimicrobial …
Conformational Changes of Anoplin, W-MreB1–9, and (KFF)3K Peptides near the Membranes
M Wojciechowska, J Miszkiewicz, J Trylska - International journal of …, 2020 - mdpi.com
Many peptides interact with biological membranes, but elucidating these interactions is
challenging because cellular membranes are complex and peptides are structurally flexible …
challenging because cellular membranes are complex and peptides are structurally flexible …
Deuterium solid state NMR studies of intact bacteria treated with antimicrobial peptides
V Booth - Frontiers in Medical Technology, 2021 - frontiersin.org
Solid state NMR has been tremendously useful in characterizing the structure and dynamics
of model membranes composed of simple lipid mixtures. Model lipid studies employing solid …
of model membranes composed of simple lipid mixtures. Model lipid studies employing solid …
Lipid II binding and transmembrane properties of various antimicrobial lanthipeptides
There has been an alarming rise in antibacterial resistant infections in recent years due to
the widespread use of antibiotics, and there is a dire need for the development of new …
the widespread use of antibiotics, and there is a dire need for the development of new …
[HTML][HTML] Translational use of homing peptides: Tumor and placental targeting
Hypothesis Tissue-specific homing peptides have been shown to improve chemotherapeutic
efficacy due to their trophism for tumor cells. Other sequences that selectively home to the …
efficacy due to their trophism for tumor cells. Other sequences that selectively home to the …
Caerin 1 Peptides, the Potential Jack‐of‐All‐Trades for the Multiple Antibiotic‐Resistant Bacterial Infection Treatment and Cancer Immunotherapy
L Xiao, X Yang, J Li, P Zhang, S Tang… - BioMed Research …, 2022 - Wiley Online Library
Antibiotic resistance‐related bacterial infections and cancers become huge challenges in
human health in the 21st century. A number of naturally derived antimicrobial peptides …
human health in the 21st century. A number of naturally derived antimicrobial peptides …
Investigating Penetration and Antimicrobial Activity of Vector-Bicycle Conjugates
A Hadjicharalambous, H Newman, N Lewis… - ACS Infectious …, 2024 - ACS Publications
Growing antibiotic resistance is rapidly threatening the efficacy of treatments for Gram-
negative infections. Bicycle molecules, constrained bicyclic peptides from diverse libraries …
negative infections. Bicycle molecules, constrained bicyclic peptides from diverse libraries …
What's the defect? Using mass defects to study oligomerization of membrane proteins and peptides in nanodiscs with native mass spectrometry
JA Townsend, MT Marty - Methods, 2023 - Elsevier
Many membrane proteins form functional complexes that are either homo-or hetero-
oligomeric. However, it is challenging to characterize membrane protein oligomerization in …
oligomeric. However, it is challenging to characterize membrane protein oligomerization in …
The application progress of peptides in drug delivery systems in the past decade
B Yang, T Wang, Y Yang, H Zhu, J Li - Journal of Drug Delivery Science …, 2021 - Elsevier
Peptides are compounds formed by linking 20 natural amino acids through amide bonds,
which widely exist in organisms. Thanks to their excellent biological activity …
which widely exist in organisms. Thanks to their excellent biological activity …
Tachyplesin I and its derivatives: A pharmaco-chemical perspective on their antimicrobial and antitumor potential
S Lu, J Lin, J Jin, L Zhang, Y Guan, H Chen… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Increasing evidence suggests that intratumor microbiota are an intrinsic
component in the tumor microenvironment across multiple cancer types, and that there is a …
component in the tumor microenvironment across multiple cancer types, and that there is a …