Nature-inspired micropatterns

Y Wang, G Zheng, N Jiang, G Ying, Y Li, X Cai… - Nature Reviews …, 2023 - nature.com
Micropatterned materials have developed in nature over 3.8 billion years, with remarkable
performance. Nature inspiration is the process of understanding biological mechanisms and …

Three‐dimensional multicellular biomaterial platforms for biomedical application

J Hao, C Qin, C Wu - Interdisciplinary Materials, 2023 - Wiley Online Library
Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …

Advances in screening hyperthermic nanomedicines in 3D tumor models

JF Soeiro, FL Sousa, MV Monteiro, VM Gaspar… - Nanoscale …, 2024 - pubs.rsc.org
Hyperthermic nanomedicines are particularly relevant for tackling human cancer, providing
a valuable alternative to conventional therapeutics. The early-stage preclinical performance …

Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids

Z Sun, Z Chen, M Yin, X Wu, B Guo, X Cheng, R Quan… - Cell Stem Cell, 2024 - cell.com
Neonatal spinal cord tissues exhibit remarkable regenerative capabilities as compared to
adult spinal cord tissues after injury, but the role of extracellular matrix (ECM) in this process …

Three-dimensional bioprinting of organoids: Past, present, and prospective

M Cabral, K Cheng, D Zhu - Tissue Engineering Part A, 2024 - liebertpub.com
Organoids are three-dimensional (3D) in vitro tissue models that are derived from stem cells
and can closely mimic the structure and function of human organs. The ability to create …

In Situ Detection of Neuroinflammation Using Multicellular 3D Neurovascular‐Unit‐on‐a‐Chip

JH Choi, HK Choi, KB Lee - Advanced Functional Materials, 2023 - Wiley Online Library
The human neurovascular system is a complex network of blood vessels and brain cells that
is essential to the proper functioning of the brain. Researchers have become increasingly …

[HTML][HTML] Human organoids-on-chips for biomedical research and applications

H Wang, X Ning, F Zhao, H Zhao, D Li - Theranostics, 2024 - ncbi.nlm.nih.gov
Human organoids-on-chips (OrgOCs) are the synergism of human organoids (HOs)
technology and microfluidic organs-on-chips (OOCs). OOCs can mimic extrinsic …

Biomimetic cell culture for cell adhesive propagation for tissue engineering strategies

Q Luo, K Shang, J Zhu, Z Wu, T Cao, AAQ Ahmed… - Materials …, 2023 - pubs.rsc.org
Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

Diffusion-based culture and real-time impedance monitoring of tumor spheroids in hydrogel microwells of a suspended membrane under microfluidic conditions

W Wang, Y Liu, X Huang, F Liang, H Luo, Z Mao, J Shi… - Talanta, 2024 - Elsevier
Tumor spheroids are widely studied for in vitro modeling of tumor growth and responses to
anticancer drugs. However, current methods are mostly limited to static and perfusion-based …

Neuropathogenesis-on-chips for neurodegenerative diseases

S Amartumur, H Nguyen, T Huynh, TS Kim… - Nature …, 2024 - nature.com
Developing diagnostics and treatments for neurodegenerative diseases (NDs) is
challenging due to multifactorial pathogenesis that progresses gradually. Advanced in vitro …