[HTML][HTML] A comprehensive review of risk factors for venous thromboembolism: from epidemiology to pathophysiology

D Pastori, VM Cormaci, S Marucci, G Franchino… - International Journal of …, 2023 - mdpi.com
Venous thromboembolism (VTE) is the third most common cause of death worldwide. The
incidence of VTE varies according to different countries, ranging from 1–2 per 1000 person …

Diagnosis and management of the antiphospholipid syndrome

D Garcia, D Erkan - New England Journal of Medicine, 2018 - Mass Medical Soc
Antiphospholipid Syndrome Antiphospholipid antibodies can induce endothelial-cell,
complement, platelet, neutrophil, and monocyte activation, leading to thrombosis, renal …

Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19

Y Zuo, SK Estes, RA Ali, AA Gandhi… - Science translational …, 2020 - science.org
Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung
histopathology often reveals fibrin-based blockages in the small blood vessels of patients …

Direct oral anticoagulants vs vitamin K antagonists in patients with antiphospholipid syndromes: meta-analysis of randomized trials

CD Khairani, A Bejjani, G Piazza, D Jimenez… - Journal of the American …, 2023 - jacc.org
Background The efficacy and safety of direct oral anticoagulants (DOACs) for patients with
thrombotic antiphospholipid syndrome remain controversial. Objectives The authors …

Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS

S Chaturvedi, EM Braunstein, X Yuan… - Blood, The Journal …, 2020 - ashpublications.org
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I …

The pathogenesis of the antiphospholipid syndrome

B Giannakopoulos, SA Krilis - New England Journal of Medicine, 2013 - Mass Medical Soc
The antiphospholipid syndrome is a prothrombotic disorder associated with autoantibodies.
It is associated with obstetrical complications (mainly spontaneous abortion) as well as …

[HTML][HTML] Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH

KMJ Devreese, TL Ortel, V Pengo, B De Laat - Journal of thrombosis and …, 2018 - Elsevier
Currently, we use the classification criteria for antiphospholipid syndrome (APS) formulated
during the consensus conference in Sapporo and revised in Sydney 1. Classification criteria …

Antiphospholipid antibodies in COVID-19: a meta-analysis and systematic review

M Taha, L Samavati - RMD open, 2021 - rmdopen.bmj.com
Background Many studies reported high prevalence of antiphospholipid antibodies (aPL) in
patients with COVID-19 raising questions about its true prevalence and its clinical impact on …

Neutrophil extracellular trap (NET) impact on deep vein thrombosis

TA Fuchs, A Brill, DD Wagner - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
Deep vein thrombosis (DVT) is a major health problem that requires improved prophylaxis
and treatment. Inflammatory conditions such as infection, cancer, and autoimmune diseases …