Pericytes, as a key cellular part of the blood-brain barrier, play an important role in the
maintenance of brain neurovascular unit. These cells participate in brain homeostasis by …

HIV infection is associated with comorbidities that are likely to be driven not only by HIV
itself, but also by the toxicity of long-term use of antiretroviral therapy (ART). Indeed …

Background Neurological complications are common in patients affected by COVID-19 due
to the ability of SARS-CoV-2 to infect brains. While the mechanisms of this process are not …

Pericytes are multifunctional cells wrapped around endothelial cells via cytoplasmic
processes that extend along the abluminal surface of the endothelium. The interactions …

The blood–brain barrier (BBB) selectively regulates the cellular exchange of
macromolecules between the circulation and the central nervous system (CNS). Here, we …

Pericytes are specialized cells located in close proximity to endothelial cells within the
microvasculature. They play a crucial role in regulating blood flow, stabilizing vessel walls …

The blood–brain barrier (BBB) is essential for the homeostasis of the central nervous system
(CNS). Functions of the BBB are performed by the neurovascular unit (NVU), which consists …

Viruses may exploit the cardiovascular system to facilitate transmission or within-host
dissemination, and the symptoms of many viral diseases stem at least in part from a loss of …

Cocaine, a known psychostimulant, results in oxidative stress and inflammation. Recent
studies from our group have shown that cocaine induces inflammation in glial cells. Our …

People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and
major depressive disorder (MDD) versus the general population. The enzyme neutral …