Yeast surface display (YSD) is a “whole-cell” platform used for the heterologous expression
of proteins immobilized on the yeast's cell surface. YSD combines the advantages …

Abstract Coronavirus disease 2019 (COVID-19) represents an unmet clinical need, due to a
high mortality rate, rapid mutation rate in the virus, increased chances of reinfection, lack of …

SARS coronavirus 2 is neutralized by proteins that block receptor‐binding sites on spikes
that project from the viral envelope. In particular, substantial research investment has …

Deep mutational scanning or deep mutagenesis is a powerful tool for understanding the
sequence diversity available to viruses for adaptation in a laboratory setting. It generally …

SARS coronavirus 2 (SARS-CoV-2) invades the human body by binding to major receptors
such as ACE2 via its S-spike protein, so the interaction of receptor-binding sites has been a …

Saccharomyces cerevisiae is a powerful system for the expression of genome-wide or
combinatorial libraries for diverse types of screening. However, expressing large libraries in …

Angiotensin-converting enzyme II (ACE2) is a monocarboxypeptidase expressed throughout
multiple tissues and its catalysis of bioactive peptides regulates the renin-angiotensin …

Corona virus disease of 2019 (COVID-19) caused by severe acute respiratory syndrome
corona virus 2 (SARS-CoV-2) has caused a massive health crisis across the globe, with …

Deep mutational scanning (DMS) experiments have been performed on SARS-CoV-2's
spike receptor-binding domain (RBD) and human angiotensin-converting enzyme 2 (ACE2) …

Saccharomyces cerevisiae is a powerful system for the expression of genome-wide or
combinatorial libraries for diverse types of screening. However, expressing large libraries in …