The challenges and applications of nanotechnology against bacterial resistance

Z Lei, A Karim - Journal of Veterinary Pharmacology and …, 2021 - Wiley Online Library
Bacterial resistance to the antibiotics develops rapidly and is increasingly serious health
concern in the world. It is an insoluble topic due to the multiple resistant mechanisms. The …

meso-Tetrahydroxyphenylchlorin-Conjugated Gold Nanoparticles as a Tool To Improve Photodynamic Therapy

E Haimov, H Weitman, S Polani, H Schori… - … applied materials & …, 2018 - ACS Publications
Photodynamic therapy (PDT) is a promising therapeutic modality for cancer. However,
current protocols using bare drugs suffer from several limitations that impede its beneficial …

Photo-cross-linkable polymer dots with stable sensitizer loading and amplified singlet oxygen generation for photodynamic therapy

Y Tang, H Chen, K Chang, Z Liu, Y Wang… - … Applied Materials & …, 2017 - ACS Publications
Photodynamic therapy (PDT) is a promising treatment modality for clinical cancer therapy.
However, the therapeutic effect of PDT is strongly dependent on the property of …

High-density branched PEGylation for nanoparticle drug delivery

D Cahn, GA Duncan - Cellular and Molecular Bioengineering, 2022 - Springer
Introduction The surface modification of nanoparticles (NP) with a dense layer of
polyethylene glycol (PEG) has been widely used to improve NP circulation time …

Studying the effect of physically‐adsorbed coating polymers on the cytotoxic activity of optimized bisdemethoxycurcumin loaded‐PLGA nanoparticles

M Mehanny, RM Hathout, AS Geneidi… - Journal of Biomedical …, 2017 - Wiley Online Library
The aim of this work was to study the effect of different physically‐adsorbed coating
polymers on the cytotoxic activity of optimized bisdemethoxycurcumin (BDMC) loaded …

Nanotechnology, Light and chemical action: an effective combination to kill cancer cells

DK Deda, K Araki - Journal of the Brazilian Chemical Society, 2015 - SciELO Brasil
Photodynamic therapy (PDT) is a minimally invasive and effective procedure for treatment of
cancer, based on the combination of a drug (photosensitizer, PS), light (visible or near …

Polymeric nanoparticles for cancer photodynamic therapy

C Conte, S Maiolino, DS Pellosi, A Miro… - … systems for applications …, 2016 - Springer
In chemotherapy a fine balance between therapeutic and toxic effects needs to be found for
each patient, adapting standard combination protocols each time. Nanotherapeutics has …

Chitosan-coated poly (lactic-co-glycolic acid)-diiodinated boron-dipyrromethene nanoparticles improve tumor selectivity and stealth properties in photodynamic …

SH Voon, SX Tiew, CS Kue, HB Lee… - Journal of …, 2016 - ingentaconnect.com
Their limited solubility and lack of tumor selectivity limit the clinical usefulness of
photosensitizers. Various nanostructures have been evaluated as delivery agents for …

Folate-targeted PEGylated liposomes improve the selectivity of PDT with meta-tetra(hydroxyphenyl)-chlorin (m-THPC)

F Moret, D Scheglmann, E Reddi - Photochemical & Photobiological …, 2013 - Springer
The folate receptor (FR) is over-expressed in many human tumours and is being intensively
studied also in the field of nanomedicine as a target to enhance the selectivity of drug …

[HTML][HTML] Microfluidic 3D intestine tumor spheroid model for efficient in vitro investigation of nanoparticular formulations

L Elberskirch, T Knoll, R Königsmark, J Renner… - Journal of Drug Delivery …, 2021 - Elsevier
For the treatment of intestinal tumors by oral administration of drugs, the mucus layer of the
intestine represents a barrier, but also a target possibility for drug. The use of nanoparticular …