Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy
Q Long, P Zheng, X Zheng, W Li, L Hua, Z Yang… - Advanced drug delivery …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for
the development of vaccines and immunotherapeutic strategies against infectious and …
the development of vaccines and immunotherapeutic strategies against infectious and …
[HTML][HTML] Peptide-based vaccines for tuberculosis
W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer
Research on bacterial membrane vesicles (BMVs) is an emerging topic, and the goal is to
address whether BMVs can bring translational tools to improve current therapies. In this …
address whether BMVs can bring translational tools to improve current therapies. In this …
[HTML][HTML] Prophylactic vaccine delivery systems against epidemic infectious diseases
C Pan, H Yue, L Zhu, G Ma, H Wang - Advanced drug delivery reviews, 2021 - Elsevier
Prophylactic vaccines have evolved from traditional whole-cell vaccines to safer subunit
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …
[HTML][HTML] Biological nanoparticles in vaccine development
SM Curley, D Putnam - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Vaccines represent one of the most successful public health initiatives worldwide. However,
despite the vast number of highly effective vaccines, some infectious diseases still do not …
despite the vast number of highly effective vaccines, some infectious diseases still do not …
Lung resident memory T cells activated by oral vaccination afford comprehensive protection against pneumonic Yersinia pestis infection
AK Singh, S Majumder, X Wang, R Song… - The Journal of …, 2023 - journals.aai.org
A growing body of evidence has shown that resident memory T (T RM) cells formed in tissue
after mucosal infection or vaccination are crucial for counteracting reinfection by pathogens …
after mucosal infection or vaccination are crucial for counteracting reinfection by pathogens …
[HTML][HTML] Engineered remolding and application of bacterial membrane vesicles
L Qiao, Y Rao, K Zhu, X Rao, R Zhou - Frontiers in Microbiology, 2021 - frontiersin.org
Bacterial membrane vesicles (MVs) are produced by both Gram-positive and Gram-negative
bacteria during growth in vitro and in vivo. MVs are nanoscale vesicular structures with …
bacteria during growth in vitro and in vivo. MVs are nanoscale vesicular structures with …
Remodeling Yersinia pseudotuberculosis to generate a highly immunogenic outer membrane vesicle vaccine against pneumonic plague
X Wang, P Li, AK Singh, X Zhang… - Proceedings of the …, 2022 - National Acad Sciences
A recombinant enteric Yersinia pseudotuberculosis PB1+ strain (Yptb) was designed to
synthesize an adjuvant form of lipid A (monophosphoryl lipid A [MPLA]), and tailor an Asd+ …
synthesize an adjuvant form of lipid A (monophosphoryl lipid A [MPLA]), and tailor an Asd+ …
Outer membrane vesicles displaying a heterologous PcrV-HitA fusion antigen promote protection against pulmonary Pseudomonas aeruginosa infection
Along with surging threats and antibiotic resistance of Pseudomonas aeruginosa in health
care settings, it is imperative to develop effective vaccines against P. aeruginosa infection. In …
care settings, it is imperative to develop effective vaccines against P. aeruginosa infection. In …
[HTML][HTML] Development of a dual antigen lateral flow immunoassay for detecting Yersinia pestis
D Hau, B Wade, C Lovejoy, SG Pandit… - PLOS Neglected …, 2022 - journals.plos.org
Background Yersinia pestis is the causative agent of plague, a zoonosis associated with
small mammals. Plague is a severe disease, especially in the pneumonic and septicemic …
small mammals. Plague is a severe disease, especially in the pneumonic and septicemic …