Supramolecular assembly boosting the phototherapy performances of BODIPYs

Y Dai, J Sun, X Zhang, J Zhao, W Yang, J Zhou… - Coordination Chemistry …, 2024 - Elsevier
Phototherapies, including photodynamic therapy (PDT) and photothermal therapy (PTT),
have emerged as leading research areas in chemistry, materials science, and medicine …

Subcellular targeting strategies for protein and peptide delivery

H Su, G Rong, L Li, Y Cheng - Advanced Drug Delivery Reviews, 2024 - Elsevier
Cytosolic delivery of proteins and peptides provides opportunities for effective disease
treatment, as they can specifically modulate intracellular processes. However, most of …

Tailoring Highly Branched Poly (β-amino ester) s for Efficient and Organ-Selective mRNA Delivery

H Yong, L Lin, Z Li, R Guo, C Wang, S Liu, D Zhou - Nano Letters, 2024 - ACS Publications
Development of mRNA therapeutics necessitates targeted delivery technology, while the
clinically advanced lipid nanoparticles face difficulty for extrahepatic delivery. Herein, we …

Nano-Delivery of Immunogenic Cell Death Inducers and Immune Checkpoint Blockade Agents: Single-Nanostructure Strategies for Enhancing Immunotherapy

Y Moon, H Cho, K Kim - Pharmaceutics, 2024 - mdpi.com
Cancer immunotherapy has revolutionized oncology by harnessing the patient's immune
system to target and eliminate cancer cells. However, immune checkpoint blockades (ICBs) …

Enhancement in the therapeutic efficacy of thymoquinone by its delivery through polypropylene glycol-functionalized silver nanoparticles

DA Raja, A Bano, M Zehra, I Vohra, S Ahmed… - Colloids and Surfaces A …, 2024 - Elsevier
Metal nanoparticles with polymer capping have been used in a variety of analytical and
biological applications. In this study, highly stable silver nanoparticles (AgNPs) …

Advances in nano‐preparations for improving tetrandrine solubility and bioavailability

J Ling, J Wu, Y Cao, T Zhang, X Cao, X Ge… - Archiv der …, 2024 - Wiley Online Library
Tetrandrine (TET) is a natural bis‐benzylisoquinoline alkaloid isolated from Stephania
species with a wide range of biological and pharmacologic activities; it mainly serves as an …

Epilepsy Treatment and Diagnosis Enhanced by Current Nanomaterial Innovations: A Comprehensive Review

S He, L Zheng, J Li, S Liu - Molecular Neurobiology, 2024 - Springer
Epilepsy is a complex disease in the brain. Complete control of seizure has always been a
challenge in epilepsy treatment. Currently, clinical management primarily involves …

[HTML][HTML] Recent Advances in Photodynamic Therapy: Metal-Based Nanoparticles as Tools to Improve Cancer Therapy

S Mariano, E Carata, L Calcagnile, E Panzarini - Pharmaceutics, 2024 - mdpi.com
Cancer remains a significant global health challenge, with traditional therapies like surgery,
chemotherapy, and radiation often accompanied by systemic toxicity and damage to healthy …

Polydopamine-Coated Zn-MOF-74 Nanocarriers: Versatile Drug Delivery Systems with Enhanced Biocompatibility and Cancer Therapeutic Efficacy

A Kazemi, MH Afshari, H Baesmat, B Bozorgnia… - Journal of Inorganic and …, 2024 - Springer
While MOF-74 drug delivery platforms are known for their high drug loading capacity (DLC)
and efficiency (DLE), surface chemistry modifications can further enhance their performance …

Targeted Antisense Oligonucleotide-Mediated Skipping of Murine Postn Exon 17 Partially Addresses Fibrosis in D2.mdx Mice

J Trundle, N Lu-Nguyen, A Malerba… - International Journal of …, 2024 - mdpi.com
Periostin, a multifunctional 90 kDa protein, plays a pivotal role in the pathogenesis of fibrosis
across various tissues, including skeletal muscle. It operates within the transforming growth …