Next-generation sequencing and global data sharing challenge many of the governance
mechanisms currently in place to protect the privacy of research participants. These …

Summary The International Human Epigenome Consortium (IHEC) coordinates the
production of reference epigenome maps through the characterization of the regulome …

Over the past two decades, the development of methods for visualizing and analysing
specimens digitally, in three and even four dimensions, has transformed the study of living …

The publication and open exchange of knowledge and material form the backbone of
scientific progress and reproducibility and are obligatory for publicly funded research …

Background With more than 30,000 species, fish—including bony, jawless, and
cartilaginous fish—are the largest vertebrate group, and include some of the earliest …

Until recently, the construction of a reference genome was performed using Sanger
sequencing alone. The emergence of next‐generation sequencing platforms now means …

The world is experiencing more frequent, deadly and costly disasters. Disasters are
increasingly uncertain and complex due to rapid environmental and socio-economic …

Biobanks can have a pivotal role in elucidating disease etiology, translation, and advancing
public health. However, meeting these challenges hinges on a critical shift in the way …

Abstract The Bermuda Principles for DNA sequence data sharing are an enduring legacy of
the Human Genome Project (HGP). They were adopted by the HGP at a strategy meeting in …

Background The pig genome is being sequenced and characterised under the auspices of
the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid …