prevention, diagnosis and management of COVID‐19 in the IBD patient

AH Al‐Ani, RE Prentice, CA Rentsch… - Alimentary …, 2020 - Wiley Online Library
Background The current COVID‐19 pandemic, caused by SARS‐CoV‐2, has emerged as a
public health emergency. All nations are seriously challenged as the virus spreads rapidly …

Current evidence and clinical relevance of drug-microbiota interactions in inflammatory bowel disease

HEF Becker, K Demers, LJJ Derijks… - Frontiers in …, 2023 - frontiersin.org
Background Inflammatory bowel disease (IBD) is a chronic relapsing-remitting disease. An
adverse immune reaction toward the intestinal microbiota is involved in the pathophysiology …

Personalized medicine of monoclonal antibodies in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring, and beyond

A Di Paolo, G Luci - Frontiers in Pharmacology, 2021 - frontiersin.org
The pharmacotherapy of inflammatory bowel diseases (Crohn's disease and ulcerative
colitis) has experienced significant progress with the advent of monoclonal antibodies …

Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies

M Simsek, DS Deben, CS Horjus… - Alimentary …, 2019 - Wiley Online Library
Background Tioguanine (or thioguanine) is an alternative drug for IBD patients who fail prior
conventional immunomodulating therapy. Aim To report effectiveness, safety and …

Point-of-care therapeutic drug monitoring of tumour necrosis factor-α inhibitors using a single step immunoassay

EA van Aalen, IR de Vries, ETL Hanckmann… - Sensors & …, 2023 - pubs.rsc.org
Therapeutic drug monitoring (TDM) of tumor necrosis factor-α (TNFα)-inhibitors adalimumab
and infliximab is important to establish optimal drug dose and maximize treatment efficacy …

Symptoms of anxiety and depression associated with steroid efficacy and clinical outcomes in patients with inflammatory bowel disease

S Duan, Y Yang, Y Cao, P Chen, C Liang… - Frontiers in …, 2023 - frontiersin.org
Background Anxiety and depression symptoms are very common in patients with
inflammatory bowel disease (IBD). We aimed to explore the impact of anxiety and …

Therapeutic drug monitoring of vedolizumab in inflammatory bowel disease patients during maintenance treatment—TUMMY study

M Sivridaş, RH Creemers, DR Wong, PJ Boekema… - Pharmaceutics, 2023 - mdpi.com
There are limited data on therapeutic drug monitoring (TDM) in inflammatory bowel disease
(IBD) patients treated with vedolizumab (VDZ). Although an exposure–response relation has …

Targeting pathophysiological changes using biomaterials-based drug delivery systems: A key to managing inflammatory bowel disease

S Mohajeri, S Moayedi, S Mohajeri… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a gastrointestinal disorder, affecting about several
million people worldwide. Current treatments fail to adequately control some clinical …

Achieving mucosal healing in inflammatory bowel diseases: which drug concentrations need to be targeted?

N Van den Berghe, A Gils… - Clinical Pharmacology & …, 2019 - Wiley Online Library
Biologicals introduced a major shift in the treatment of patients suffering from inflammatory
bowel diseases. Despite providing a tight disease control for many patients, a considerable …

Current status and future perspectives on the use of therapeutic drug monitoring of thiopurine metabolites in patients with inflammatory bowel disease

DS Deben, DR Wong… - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction Despite new treatment options for inflammatory bowel disease (IBD),
conventional thiopurines remain a common treatment option for maintaining remission …