[PDF][PDF] From gene-discovery to gene-tailored clinical management: 25 years of research in channelopathies and cardiomyopathies

L Crotti, P Brugada, H Calkins, P Chevalier, G Conte… - Europace, 2023 - academic.oup.com
In the early nineties, few years before the birth of Europace, the clinical and scientific world
of familial arrhythmogenic conditions was revolutionized by the identification of the first …

Risk stratification of sudden cardiac death: a review

J Tfelt-Hansen, R Garcia, C Albert, J Merino, A Krahn… - Europace, 2023 - academic.oup.com
Sudden cardiac death (SCD) is responsible for several millions of deaths every year and
remains a major health problem. To reduce this burden, diagnosing and identification of …

Fresh and frozen cardiac tissue are comparable in DNA methylation array β-values, but formalin-fixed, paraffin-embedded tissue may overestimate DNA methylation …

ME Dupont, SB Jacobsen, SNN Christiansen… - Scientific Reports, 2023 - nature.com
Untreated fresh cardiac tissue is the optimal tissue material for investigating DNA
methylation patterns of cardiac biology and diseases. However, fresh tissue is difficult to …

Severity of Brugada syndrome disease manifestation and risk of new-onset depression or anxiety: a Danish nationwide study

CHB Jespersen, J Krøll, P Bhardwaj, BG Winkel… - Europace, 2023 - academic.oup.com
Aims Reduced psychological health is associated with adverse patient outcomes and higher
mortality. We aimed to examine if a Brugada syndrome (BrS) diagnosis and symptomatic …

Cardiac tamponades related to interventional electrophysiology procedures are associated with higher risk of short-term hospitalization for pericarditis but favourable …

G von Olshausen, F Tabrizi, R Sigurjónsdóttir… - Europace, 2023 - academic.oup.com
Aims To investigate the association of iatrogenic cardiac tamponades as a complication of
invasive electrophysiology procedures (EPs) and mortality as well as serious cardiovascular …

Autopsy of all young sudden death cases is important to increase survival in family members left behind

TH Lynge, CM Albert, C Basso, R Garcia… - EP …, 2024 - academic.oup.com
Sudden cardiac death (SCD) is an important public health problem worldwide, accounting
for an estimated 6–20% of total mortality. A significant proportion of SCD is caused by …

Telehealth of cardiac devices for CVD treatment

S Shelke, K Veerubhotla, Y Lee… - Biotechnology and …, 2024 - Wiley Online Library
This review covers currently available cardiac implantable electronic devices (CIEDs) as
well as updated progress in realtime monitoring techniques for CIEDs. A variety of …

Understanding the incidence of atrial fibrillation and stroke in hypertrophic cardiomyopathy patients: insights from Danish nationwide registries

CR Zörner, AM Schjerning, MK Jensen… - EP …, 2024 - academic.oup.com
Aims The treatment of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) can be
challenging since AF aggravates symptoms and increases the risk of stroke. Which factors …

RNA sequencing of formalin fixed paraffin-embedded heart tissue provides transcriptomic information about chemotherapy-induced cardiotoxicity

VK Todorova, MA Bauer, G Azhar, JY Wei - Pathology-Research and …, 2024 - Elsevier
Gene expression of formalin-fixed paraffin-embedded (FFPE) tissue may serve for molecular
studies on cardiovascular diseases. Chemotherapeutics, such as doxorubicin (DOX) may …

Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction

L Vicent, J Álvarez-García, R Vazquez-Garcia… - Journal of Clinical …, 2023 - mdpi.com
Our aim was to determine the prognostic impact of coronary artery disease (CAD) on heart
failure with reduced ejection fraction (HFrEF) mortality and readmissions. From a …