Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Gamma glutamyl transferase

JB Whitfield - Critical reviews in clinical laboratory sciences, 2001 - Taylor & Francis
Referee: R. Rej, New York State Dept. of Health, Albany, NY Serum gamma-glutamyl
transferase (GGT) has been widely used as an index of liver dysfunction and marker of …

The association between elevated lipid profile and liver enzymes: a study on Bangladeshi adults

RR Kathak, AH Sumon, NH Molla, M Hasan, R Miah… - Scientific reports, 2022 - nature.com
Dyslipidemia, a major contributor to cardiovascular diseases, is rapidly increasing in Asian
countries including Bangladesh. In addition to the cardiovascular system, abnormal lipid …

An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures

GJ Dugbartey, LJ Peppone, IAM de Graaf - Toxicology, 2016 - Elsevier
Cisplatin is currently one of the most widely-used chemotherapeutic agents against various
malignancies. Its clinical application is limited, however, by inherent renal and cardiac …

Gamma-glutamyl transpeptidase: redox regulation and drug resistance

MH Hanigan - Advances in cancer research, 2014 - Elsevier
The expression of gamma-glutamyl transpeptidase (GGT) is essential to maintaining
cysteine levels in the body. GGT is a cell surface enzyme that hydrolyzes the gamma …

[HTML][HTML] Cisplatin nephrotoxicity: molecular mechanisms

MH Hanigan, P Devarajan - Cancer therapy, 2003 - ncbi.nlm.nih.gov
Cisplatin is one of the most widely used chemotherapeutic agents for the treatment of
several human malignancies. The efficacy of cisplatin is dose dependent, but the significant …

S-glutathionylation: from molecular mechanisms to health outcomes

Y Xiong, JD Uys, KD Tew… - Antioxidants & redox …, 2011 - liebertpub.com
Redox homeostasis governs a number of critical cellular processes. In turn, imbalances in
pathways that control oxidative and reductive conditions have been linked to a number of …

Alanine aminotransferase, γ-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis

A Fraser, R Harris, N Sattar, S Ebrahim… - Diabetes …, 2009 - Am Diabetes Assoc
OBJECTIVE To estimate and compare associations of alanine aminotransferase (ALT) and γ-
glutamyltransferase (GGT) with incident diabetes. RESEARCH DESIGN AND METHODS …

Liver enzymes, the metabolic syndrome, and incident diabetes: the Mexico City diabetes study

M Nannipieri, C Gonzales, S Baldi, R Posadas… - Diabetes …, 2005 - Am Diabetes Assoc
OBJECTIVE—To test the hypothesis that enzymes conventionally associated with liver
dysfunction (aspartate aminotransferase, alanine aminotransferase, γ-glutamyltransferase …

Gamma-glutamyltransferase and diabetes—a 4 year follow-up study

DH Lee, MH Ha, JH Kim, DC Christiani, MD Gross… - Diabetologia, 2003 - Springer
Abstract Aims/Hypothesis Gamma-glutamyltransferase (GGT) is located on the external
surface of most cells and mediates the uptake of gluthathione, an important component of …