Cerebellar Purkinje cells exhibit a unique type of synaptic plasticity, namely, long-term
depression (LTD). When two inputs to a Purkinje cell, one from a climbing fiber and the other …

Classical conditioning of the eyeblink reflex to a neutral stimulus that predicts an aversive
stimulus is a basic form of associative learning. Acquisition and retention of this learned …

The cerebellum and its associated circuitry constitutes the entire essential neuronal system
for classical conditioning of eye-blink and other discrete responses (eg limb flexion) learned …

Associative learning in the cerebellum underlies motor memories and probably also
cognitive associations. Pavlovian eyeblink conditioning, a widely used experimental model …

Pavlovian eyeblink conditioning has been used extensively as a model system for
examining the neural mechanisms underlying associative learning. Delay eyeblink …

Recent evidence from cerebellum-dependent motor learning and amygdala-dependent fear
conditioning indicates that, despite being mediated by different brain systems, these forms of …

The phenomenon of savings (the ability to relearn faster than the first time) is a familiar
property of many learning systems. The utility of savings makes its underlying mechanisms …

The level of electrotonic coupling in the inferior olive is extremely high, but its functional role
in cerebellar motor control remains elusive. Here, we subjected mice that lack olivary …

The notion that the olivocerebellar system is crucial for motor learning is well established. In
recent years, it has become evident that there can be many forms of both synaptic and non …

Behavioral and computational studies predict that synaptic plasticity of excitatory mossy fiber
inputs to cerebellar nuclear neurons is required for associative learning, but standard …