The underlying pathophysiology and therapeutic approaches for osteoporosis

H Awasthi, D Mani, D Singh… - Medicinal research …, 2018 - Wiley Online Library
With an increase in the ageing population worldwide, the prevalence of osteoporosis
increases at an alarming rate in both male and female irrespective of their ethnicity. At …

Interactions between osteopontin and vascular endothelial growth factor: Implications for cancer

D Ramchandani, GF Weber - Biochimica et Biophysica Acta (BBA)-Reviews …, 2015 - Elsevier
For this comprehensive review, 257 publications with the keywords “osteopontin” or “OPN”
and “vascular endothelial growth factor” or “VEGF” in PubMed were screened (time frame …

Alterations of bone material properties in adult patients with X-linked hypophosphatemia (XLH)

N Fratzl-Zelman, S Gamsjaeger, S Blouin… - Journal of structural …, 2020 - Elsevier
X-linked hypophosphatemia (XLH) caused by PHEX mutations results in elevated serum
FGF23 levels, renal phosphate wasting and low 1, 25-dihydroxyvitamin D. The …

Molecular signature of biological aggressiveness in clear cell sarcoma of the kidney (CCSK)

M Fiore, A Taddia, V Indio, SN Bertuccio… - International Journal of …, 2023 - mdpi.com
Clear cell sarcoma of the kidney (CCSK) is a rare pediatric renal tumor with a worse
prognosis than Wilms' tumor. Although recently, BCOR internal tandem duplication (ITD) has …

Enhanced healing of surgical periodontal defects in rats following application of a self‐assembling peptide nanofibre hydrogel

T Takeuchi, T Bizenjima, Y Ishii… - Journal of clinical …, 2016 - Wiley Online Library
Aim The aim of this study was to investigate the effects of a self‐assembling peptide (SAP)
nanofibre hydrogel on healing of surgical periodontal defects in rats. Materials and Methods …

In vitro treatment with concentrated growth factors (CGF) and sodium orthosilicate positively affects cell renewal in three different human cell lines

V Bonazza, E Borsani, B Buffoli… - Cell Biology …, 2018 - Wiley Online Library
The aim of this study was to investigate the in vitro effect of Silicon, in the soluble form of
sodium orthosilicate, combined and not with the concentrated growth factors (CGF), a …

Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization

AJ Sawyer, TR Kyriakides - Advanced drug delivery reviews, 2016 - Elsevier
Extracellular matrix is composed of a complex array of molecules that together provide
structural and functional support to cells. These properties are mainly mediated by the …

[HTML][HTML] Low-dose cadmium exposure acts on rat mesenchymal stem cells via RANKL/OPG and downregulate osteogenic differentiation genes

YJ Lv, QZ Wei, YC Zhang, R Huang, BS Li, JB Tan… - Environmental …, 2019 - Elsevier
Chronic cadmium (Cd) toxicity is a significant health concern, and the mechanism of long-
term low-dose Cd exposure on bone has not been fully elucidated till date. This study aimed …

Role of vascular calcification inhibitors in preventing vascular dysfunction and mortality in hemodialysis patients

O Gungor, I Kocyigit, MI Yilmaz, S Sezer - Seminars in dialysis, 2018 - Wiley Online Library
Cardiovascular events make up the primary cause of death in hemodialysis patients, and the
risk for cardiovascular mortality is significantly increased by vascular calcification, a …

Systemic melatonin application increases bone formation in mandibular distraction osteogenesis

I Acikan, GUL Mehmet, G Artas, F Yaman… - Brazilian oral …, 2018 - SciELO Brasil
This study aimed to investigate the effects of different doses of systemic melatonin
application on new bone formation during mandibular distraction osteogenesis (DO) in rats …