An inflammation‐associated ferroptosis signature optimizes the diagnosis, prognosis evaluation and immunotherapy options in hepatocellular carcinoma
WY Ruan, L Zhang, S Lei, ZR Zeng… - Journal of Cellular …, 2023 - Wiley Online Library
Inflammation and ferroptosis crosstalk complexly with immune microenvironment of
hepatocellular carcinoma (HCC), thus affecting the efficacy of immunotherapy. Herein, our …
hepatocellular carcinoma (HCC), thus affecting the efficacy of immunotherapy. Herein, our …
Identifying the programmed cell death index of hepatocellular carcinoma for prognosis and therapy response improvement by machine learning: a bioinformatics …
Y Shi, Y Feng, P Qiu, K Zhao, X Li, Z Deng… - Frontiers in …, 2023 - frontiersin.org
Background Despite advancements in hepatocellular carcinoma (HCC) treatments, the
prognosis for patients remains suboptimal. Cumulative evidence suggests that programmed …
prognosis for patients remains suboptimal. Cumulative evidence suggests that programmed …
[HTML][HTML] Prognosis and immunoinfiltration analysis of angiogene-related genes in grade 4 diffuse gliomas
H Liu, Z Zeng, P Sun - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Although angiogenesis critically influences the progression of solid tumors, its contribution to
highly malignant, grade 4 diffuse gliomas remains unclear. After analyzing 506 …
highly malignant, grade 4 diffuse gliomas remains unclear. After analyzing 506 …
[HTML][HTML] An immune signature to predict the prognosis of ATRX-wildtype glioma patients and guide immune checkpoint blockade therapy
W Cao, P Sun, S Luo, Z Zeng, C Xiao, W Yu… - Aging (Albany NY …, 2023 - ncbi.nlm.nih.gov
Immune and stromal cells contribute to glioma progression by infiltrating the tumor
microenvironment. We used clinical characteristics, RNA sequencing data and the …
microenvironment. We used clinical characteristics, RNA sequencing data and the …
[HTML][HTML] Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new …
C Han, J Chen, J Huang, R Zhu, J Zeng, H Yu… - Frontiers in …, 2023 - frontiersin.org
Background: A hallmark of cancer is the reprogramming of energy metabolism which causes
rapid cell growth and proliferation and the development of hepatocellular carcinoma (HCC) …
rapid cell growth and proliferation and the development of hepatocellular carcinoma (HCC) …
A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy
Z Zeng, C Hu, W Ruan, J Zhang, S Lei, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Isocitrate dehydrogenase (IDH1) is frequently mutated in glioma tissues, and this mutation
mediates specific tumor-promoting mechanisms in glioma cells. We aimed to identify specific …
mediates specific tumor-promoting mechanisms in glioma cells. We aimed to identify specific …
[HTML][HTML] Machine learning integrations for development of a T-cell-tolerance derived signature to improve the clinical outcomes and precision treatment of …
J Li, J Chen, Q Tao, J Zheng, Z Zhou - American Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is characterized by high rates of recurrence and metastasis
and poor prognosis. A recently discovered concept of T cell tolerance (TCT) has become an …
and poor prognosis. A recently discovered concept of T cell tolerance (TCT) has become an …