Nutrition, infection and stunting: the roles of deficiencies of individual nutrients and foods, and of inflammation, as determinants of reduced linear growth of children

DJ Millward - Nutrition research reviews, 2017 - cambridge.org
The regulation of linear growth by nutritional and inflammatory influences is examined in
terms of growth-plate endochondral ossification, in order to better understand stunted growth …

The growth hormone receptor: mechanism of receptor activation, cell signaling, and physiological aspects

F Dehkhoda, CMM Lee, J Medina… - Frontiers in …, 2018 - frontiersin.org
The growth hormone receptor (GHR), although most well known for regulating growth, has
many other important biological functions including regulating metabolism and controlling …

Acromegaly pathogenesis and treatment

S Melmed - The Journal of clinical investigation, 2009 - Am Soc Clin Investig
Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …

Growth hormone and insulin-like growth factor action in reproductive tissues

E Ipsa, VF Cruzat, JN Kagize, JL Yovich… - Frontiers in …, 2019 - frontiersin.org
The role of growth hormone (GH) in human fertility is widely debated with some studies
demonstrating improvements in oocyte yield, enhanced embryo quality, and in some cases …

The growth hormone signaling system: Insights into coordinating the anabolic and catabolic actions of growth hormone

HE Bergan-Roller, MA Sheridan - General and comparative endocrinology, 2018 - Elsevier
Although growth hormone (GH) is a multifunctional factor that coordinates various aspects of
feeding, reproduction, osmoregulation, and immune system function, perhaps two of its most …

The intricate role of growth hormone in metabolism

A Vijayakumar, S Yakar, D LeRoith - Frontiers in endocrinology, 2011 - frontiersin.org
Growth hormone (GH), a master regulator of somatic growth, also regulates carbohydrate
and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 …

[HTML][HTML] Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes

SLP Regan, PG Knight, JL Yovich, F Arfuso… - Fertility and sterility, 2018 - Elsevier
Objective To study the effect of aging and granulosa cell growth hormone receptor (GHR)
expression, and the effect of growth hormone (GH) co-treatment during IVF on receptor …

Growth hormone is permissive for neoplastic colon growth

V Chesnokova, S Zonis, C Zhou… - Proceedings of the …, 2016 - National Acad Sciences
Growth hormone (GH) excess in acromegaly is associated with increased precancerous
colon polyps and soft tissue adenomas, whereas short-stature humans harboring an …

Extrapituitary growth hormone

S Harvey - Endocrine, 2010 - Springer
Pituitary somatotrophs secrete growth hormone (GH) into the bloodstream, to act as a
hormone at receptor sites in most, if not all, tissues. These endocrine actions of circulating …

Non-pituitary GH regulation of the tissue microenvironment

V Chesnokova, S Melmed - Endocrine-related cancer, 2023 - erc.bioscientifica.com
Non-pituitary growth hormone (npGH) expression is well established in extrapituitary
tissues, but an understanding of the physiological role of npGH remains rather limited. Pro …