[HTML][HTML] Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care

A Tarocco, N Caroccia, G Morciano… - Cell death & …, 2019 - nature.com
Melatonin, more commonly known as the sleep hormone, is mainly secreted by the pineal
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …

[HTML][HTML] Oxygen and oxidative stress in the perinatal period

I Torres-Cuevas, A Parra-Llorca, A Sánchez-Illana… - Redox biology, 2017 - Elsevier
Fetal life evolves in a hypoxic environment. Changes in the oxygen content in utero caused
by conditions such as pre-eclampsia or type I diabetes or by oxygen supplementation to the …

Diagnosis and management of bronchopulmonary dysplasia

M Gilfillan, A Bhandari, V Bhandari - Bmj, 2021 - bmj.com
Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in infants and
is associated with increased mortality, respiratory morbidity, neurodevelopmental …

Resuscitation of preterm neonates with limited versus high oxygen strategy

VS Kapadia, LF Chalak, JE Sparks, JR Allen… - …, 2013 - publications.aap.org
OBJECTIVE: To determine whether a limited oxygen strategy (LOX) versus a high oxygen
strategy (HOX) during delivery room resuscitation decreases oxidative stress in preterm …

[HTML][HTML] Cerebral palsy

HK Graham, P Rosenbaum, N Paneth… - Nature reviews …, 2016 - ncbi.nlm.nih.gov
Cerebral palsy is the most common cause of childhood-onset, lifelong physical disability in
most countries, affecting about 1 in 500 neonates with an estimated prevalence of 17 million …

Intermittent hypoxemia and oxidative stress in preterm infants

JM Di Fiore, M Vento - Respiratory physiology & neurobiology, 2019 - Elsevier
Intermittent hypoxemia events (IH) are common in extremely preterm infants and are
associated with many poor outcomes including retinopathy or prematurity, wheezing …

Early red cell transfusion is associated with development of severe retinopathy of prematurity

C Lust, Z Vesoulis, R Jackups Jr, S Liao, R Rao… - Journal of …, 2019 - nature.com
Objective To evaluate the association between early (within 10 d) pRBC transfusion and the
development of severe ROP. Study design and Methods This was a single-center …

Colchicine protects against hyperoxic lung injury in neonatal rats

R Ozdemir, S Yurttutan, B Talim, B Uysal, O Erdeve… - Neonatology, 2012 - karger.com
Background: Bronchopulmonary dysplasia (BPD) is characterized by inflammation, fibrosis
and mucosal necrosis, which leads to emphysematous coalescence of alveoli. Objective …

Oxygen therapy of the newborn from molecular understanding to clinical practice

OD Saugstad, JL Oei, S Lakshminrusimha… - Pediatric research, 2019 - nature.com
Oxygen is one of the most critical components of life. Nature has taken billions of years to
develop optimal atmospheric oxygen concentrations for human life, evolving from very low …

The neonatal lung–physiology and ventilation

RP Neumann… - Pediatric Anesthesia, 2014 - Wiley Online Library
This review article focuses on neonatal respiratory physiology, mechanical ventilation of the
neonate and changes induced by anesthesia and surgery. Optimal ventilation techniques for …