RETRACTED: Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization

S Spence, A Fitzsimons, CR Boyd, J Kessler… - Immunity, 2013 - cell.com
Having discovered discrepancies within the scatter plots in Figures 3B and 4B of this
manuscript, the authors have had the data investigated by two independent panels …

Donor-dependent variation of human umbilical cord blood mesenchymal stem cells in response to hypoxic preconditioning and amelioration of limb ischemia

I Kang, BC Lee, SW Choi, JY Lee, JJ Kim… - … & molecular medicine, 2018 - nature.com
With the rapidly growing demand for mesenchymal stem cell (MSC) therapy, numerous
strategies using MSCs for different diseases have been studied and reported. Because of …

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity

S Galic, N Sachithanandan, TW Kay… - Biochemical …, 2014 - portlandpress.com
Overactivation of immune pathways in obesity is an important cause of insulin resistance
and thus new approaches aimed to limit inflammation or its consequences may be effective …

Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells

M Uchino, H Kojima, K Wada, M Imada, F Onoda… - BMC cancer, 2010 - Springer
Background In breast cancer cells, the metastatic cell state is strongly correlated to epithelial-
to-mesenchymal transition (EMT) and the CD44+/CD24-stem cell phenotype. However, the …

[HTML][HTML] Feedback regulation of RTK signaling in development

CL Neben, M Lo, N Jura, OD Klein - Developmental biology, 2019 - Elsevier
Precise regulation of the amplitude and duration of receptor tyrosine kinase (RTK) signaling
is critical for the execution of cellular programs and behaviors. Understanding these control …

Regulation of macrophage, dendritic cell, and microglial phenotype and function by the SOCS proteins

SM McCormick, NM Heller - Frontiers in immunology, 2015 - frontiersin.org
Macrophages are innate immune cells of dynamic phenotype that rapidly respond to
external stimuli in the microenvironment by altering their phenotype to respond to and to …

Regulation of CD4+ T‐cell polarization by suppressor of cytokine signalling proteins

CA Knosp, JA Johnston - Immunology, 2012 - Wiley Online Library
Suppressors of cytokine signalling (SOCS) proteins are induced in responses to many
stimuli and by binding to cytokine receptors and associated janus kinase (JAK) proteins …

SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses

CA Knosp, HP Carroll, J Elliott, SP Saunders… - Journal of Experimental …, 2011 - rupress.org
The incidence of allergy and asthma in developed countries is on the increase and this trend
looks likely to continue. CD4+ T helper 2 (Th2) cells are major drivers of these diseases and …

Suppressor of cytokine signaling 3 controls lysosomal routing of G‐CSF receptor

MI Irandoust, LHJ Aarts, O Roovers, J Gits… - The EMBO …, 2007 - embopress.org
The hematopoietic system provides an attractive model for studying growth factor‐controlled
expansion and differentiation of cells in relation to receptor routing and its consequences for …

Fish suppressors of cytokine signaling (SOCS): gene discovery, modulation of expression and function

T Wang, B Gorgoglione, T Maehr… - Journal of signal …, 2011 - Wiley Online Library
The intracellular suppressors of cytokine signaling (SOCS) family members, including CISH
and SOCS1 to 7 in mammals, are important regulators of cytokine signaling pathways. So …