Omics and male infertility: highlighting the application of transcriptomic data

TS Omolaoye, VA Omolaoye, RK Kandasamy… - Life, 2022 - mdpi.com
Male infertility is a multifaceted disorder affecting approximately 50% of male partners in
infertile couples. Over the years, male infertility has been diagnosed mainly through semen …

Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis

PD Nongthombam, SS Malini - Genes & Genomics, 2023 - Springer
Background Various populations have been investigated for the occurrence of two key DAZL
polymorphisms, 260A> G (rs11710967) and 386A> G (rs121918346), as well as complete …

Y chromosome microdeletions in Chinese men with infertility: prevalence, phenotypes, and intracytoplasmic sperm injection outcomes

D Chen, G Fan, X Zhu, Q Chen, X Chen, F Gao… - Reproductive Biology …, 2023 - Springer
Background The incidence of Y chromosome microdeletions varies among men with
infertility across regions and ethnicities worldwide. However, comprehensive …

Molecular genetic analysis of 1,980 cases of male infertility

M Fu, M Chen, N Guo, M Lin, Y Li… - Experimental and …, 2023 - spandidos-publications.com
The present study aimed to investigate the occurrence of chromosomal karyotype
abnormalities and azoospermia factor (AZF) microdeletion on the long arm of the Y …

Infertility in Fabry's Disease: role of hypoxia and inflammation in determining testicular damage

L Sansone, F Barreca, M Belli… - Frontiers in …, 2024 - frontiersin.org
Introduction Fabry's disease (FD) is a genetic X-linked systemic and progressive rare
disease characterized by the accumulation of globotriaosylceramide (GB3) into the …

Detection of partial and/or complete Y chromosome microdeletions of azoospermia factor a (AZFa) sub‐region in infertile Iraqi patients with azoospermia and severe …

MT S. Al‐Ouqaili, SK Al‐Ani, R Alaany… - Journal of Clinical …, 2022 - Wiley Online Library
Background This study aimed to analyze the incidence of azoospermia factor a (AZFa)
microdeletions in the Y chromosome and their association with male infertility in a …

Detection of AZF microdeletions and analysis of reproductive hormonal profiles in Hainan men undergoing assisted reproductive technology

Q He, Y Zhang, M Song, Y Zhou, D Lin, Y Ma, F Sun… - BMC urology, 2024 - Springer
Background Male infertility has become a global health problem, and genetic factors are one
of the essential causes. Y chromosome microdeletion is the leading genetic factor cause of …

Optimization of Multiplex-PCR Technique To Determine Azf Deletions in infertility Male Patients

TN Thanh, ST Tien, PN Van, SD Thai… - … Journal of General …, 2024 - Taylor & Francis
Background To optimize the multiplex polymerase chain reaction (M-PCR) technique to
diagnose microdeletions of azoospermia factors (AZF) on the Y chromosome and initially …

The paternal role in pregnancy loss

W Muncey, M Scott, RB Lathi, ML Eisenberg - Andrology, 2024 - Wiley Online Library
In this comprehensive review, the intricate relationship between paternal factors and
pregnancy loss is examined. While pregnancy loss has historically been predominantly …

Identification of Y-SNPs within ovine MSY region and their association with testicular size

S Pei, X Cao, X Wang, F Li, X Yue - Theriogenology, 2023 - Elsevier
The screening of genomic variations within the male-specific region of the mammalian Y
chromosome (MSY) is one of the most effective ways to investigate paternal evolutionary …