Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Since the end of 2019, the whole world has been struggling with the pandemic of the new
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Available evidence …

Background Despite the increasing knowledge of the etiology of neuropathic pain, this type
of chronic pain is resistant to available analgesics in approximately 50% of patients and …

Neuropathic pain due to a lesion or a disease of the somatosensory system often affects
older people presenting several comorbidities. Moreover, elderly patients are often poly …

Background: Neuropathic pain is an injury or disease of the central and/or peripheral
somatosensory nervous system, and it has a significant impact on quality of life, especially …

The wingless-related integration site (Wnt) signaling pathway plays an essential role in
embryonic development and nervous system regulation. It is critically involved in multiple …

Neuropathic pain results from lesions or diseases of the somatosensory nervous system and
it remains largely difficult to treat. Peripheral neuropathic pain originates from injury to the …

Background Neuropathic pain is related to the sustained activation of neuroglial cells and
the production of proinflammatory cytokines in the spinal dorsal horn. However, the clinical …

Postherpetic neuralgia (PHN) is the most troublesome side effect of Herpes Zoster (HZ),
which mainly affects the elderly and immunocompromised populations. Despite the current …

Chronic pain is one of the leading causes of disability and disease burden worldwide,
accounting for a prevalence between 6.9% and 10% in the general population …