In vitro evaluation of the neuroprotective potential of Olea dioica against Aβ peptide-induced toxicity in human neuroblastoma SH-SY5Y cells

PG Kenchappa, Y Karthik, PD Vijendra… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a type of neurodegenerative disease, associated with the
hastening of ROS, acetylcholinesterase (AChE) activity, and amyloid β peptides plaques in …

Rosavin thwarts amyloid-β-induced macromolecular damages and neurotoxicity, exhibiting anti-Alzheimer's disease activity in Wister rat model

M Huang, R Sui, L Zhang, Y Zhu, X Yuan, H Jiang… - …, 2024 - Springer
Lately, interest surrounding the utilization of plant-derived compounds as a viable beneficial
approach for treating Alzheimer's disease (AD) has significantly increased. This study aimed …

Side effects based network construction and drug repositioning of ropinirole as a potential molecule for Alzheimer's disease: an in-silico, in-vitro, and in-vivo study

A Chakkittukandiyil, S Chakraborty… - Journal of …, 2023 - Taylor & Francis
Alzheimer's disease (AD) is the leading cause of dementia in older adults. Drug
repositioning is a process of finding new therapeutic applications for existing drugs. One of …

Amelioration effects of Cirsium japonicum var. maackii extract/fractions on amyloid beta 25–35-induced neurotoxicity in SH-SY5Y cells and identification of the main …

MJ Kim, JH Kim, JH Kim, S Lee, EJ Cho - Food & Function, 2020 - pubs.rsc.org
Amyloid beta (Aβ) is a neurotoxic peptide, and the accumulation of Aβ in the brain is the
major characteristic of Alzheimer's disease (AD). Recently, the beneficial effects of Cirsium …

Alterations in Bacterial Metabolism Contribute to the Lifespan Extension Exerted by Guarana in Caenorhabditis elegans

I Reigada, K Kapp, C Maynard, D Weinkove, MS Valero… - Nutrients, 2022 - mdpi.com
Guarana (Paullinia cupana) is a widely consumed nutraceutical with various health benefits
supported by scientific evidence. However, its indirect health impacts through the gut …

[HTML][HTML] Validation of the protective effects of Lonicera japonica polysaccharide on lipopolysaccharide-induced learning and memory impairments via regulation of …

J Wang, P Liu, X Huang, X Wu - Annals of Palliative Medicine, 2021 - apm.amegroups.org
Background: Learning and memory impairments are important indexes in assessing
Alzheimer's disease (AD). Lonicera japonica (L. japonica), a traditional Chinese herbal …

A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer's Disease

D Vicente-Zurdo, E Gómez-Mejía… - International Journal of …, 2024 - mdpi.com
Alzheimer's Disease (AD), a prevalent neurodegenerative disorder, is the primary cause of
dementia. Despite significant advancements in neuroscience, a definitive cure or treatment …

[HTML][HTML] In vivo anti cancer potential of pyrogallol in murine model of colon cancer

S Revathi, FL Hakkim, NR Kumar… - Asian Pacific journal …, 2019 - ncbi.nlm.nih.gov
Background: Colon cancer is aggressive and it causes 0.5 million deaths per year.
Practicing natural medicines for cancer treatment is safer than conventional drugs. World …

Antioxidant Activity of Flavonoid Rich Fraction of Ligaria cuneifolia (Loranthaceae)

C Dobrecky, T Marchini, R Ricco… - Chemistry & …, 2020 - Wiley Online Library
Abstract Ligaria cuneifolia (Ruiz & Pav.) Tiegh.(Loranthaceae), the 'Argentine mistletoe', is a
hemiparasite species largely used in folk medicine. The aim of this study was to evaluate the …

pH stimulus-responsive hybrid nanoparticles: A system designed for follicular delivery of brazilian plant-derived 5-alpha-reductase enzyme inhibitors

RP Morais, CC de Oliveira, IC Riegel-Vidotti… - International Journal of …, 2024 - Elsevier
Abstract The 5-alpha-reductase enzyme, present in pilosebaceous units, plays a crucial role
in the appearance of cutaneous hyperandrogenism manifestations (hirsutism, acne, and …