Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …

Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

DNA methylation microarrays can be employed to interrogate cell-type composition in
complex tissues. Here, we expand reference-based deconvolution of blood DNA …

The immune system plays a significant role in multiple sclerosis. While MS was historically
thought to be T cell-mediated, multiple pieces of evidence now support the view that B cells …

SARS-CoV2 infection is responsible for a complex clinical syndrome, named Coronavirus
Disease 2019 (COVID-19), whose main consequences are severe pneumonia and acute …

Background Intermittent fasting or calorie restriction (CR) diets provide anti-inflammatory
and neuroprotective advantages in models of multiple sclerosis (MS); data in humans are …

Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …

Our understanding of the role of innate and adaptive immune cell function in brain health
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …

Roles for viral infections and aberrant immune responses in driving localized
neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of …