Perinatal brain injury is the leading cause of neurological mortality and morbidity in
childhood ranging from motor and cognitive impairment to behavioural and neuropsychiatric …

Myeloid cells comprise the majority of immune cells in tumors, contributing to tumor growth
and therapeutic resistance. Incomplete understanding of myeloid cells response to tumor …

The fetal inflammatory response syndrome (FIRS) is characterized by umbilical cord
inflammation and elevated fetal pro-inflammatory cytokines. Surviving neonates, especially …

The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Background: Microglia are key mediators of inflammation during perinatal brain injury. As
shown experimentally after inflammation-sensitized hypoxic ischemic (HI) brain injury …

Autism comprises a broad range of neurodevelopmental disorders characterized by social
communication deficits and repetitive and stereotyped behaviors. Chemokine receptor …

After traumatic brain injury (TBI), some people have worse recovery than others. Single
nucleotide polymorphisms (SNPs) in Apolipoprotein E (APOE) are known to increase risk for …

The result of a deprivation of oxygen and glucose to the brain, hypoxic–ischemic
encephalopathy (HIE), remains the most common cause of death and disability in human …

Background Chorioamnionitis (CHORIO) is a principal risk factor for preterm birth and is the
most common pathological abnormality found in the placentae of preterm infants. CHORIO …

Background Abnormal diffusion within white matter (WM) tracts has been linked to cognitive
impairment in children with fetal alcohol spectrum disorder. Whether changes to myelin …