Among the most extensively researched processes in the development and treatment of
cancer is inflammatory condition. Although acute inflammation is essential for the wound …

Nanoparticles (NPs) modified by cell membranes represent an emerging biomimetic
platform that can mimic the innate biological functions resulting from the various cell …

Recent data have expanded the concept that inflammation is a critical component of tumour
progression. Many cancers arise from sites of infection, chronic irritation and inflammation. It …

Tumour-associated macrophages (TAM) represent the major inflammatory component of the
stroma of many tumours, and can affect different aspects of the neoplastic tissue. Many …

The link between inflammation and cancer proposed more than a century ago by Rudolf
Virchow, who noticed the infiltration of leukocytes in malignant tissues, has recently found a …

Although interleukin-18 is structurally homologous to IL-1 and its receptor belongs to the IL-
1R/Toll-like receptor (TLR) superfamily, its function is quite different from that of IL-1. IL-18 is …

As prostate cancer and aberrant changes in reactive oxygen species (ROS) become more
common with aging, ROS signaling may play an important role in the development and …

IL-18 is a potent proinflammatory cytokine able to induce IFNγ, GM-CSF, TNFα and IL-1 in
immunocompetent cells, to activate killing by lymphocytes, and to up-regulate the …

Inflammatory cell infiltration of tumors contributes either positively or negatively to tumor
invasion, growth, metastasis, and patient outcomes, creating a Dr. Jekyll or Mr. Hyde …

It is well established that cancer is a progressive disease, occurring in a series of well-
defined steps, typically arising as a consequence of activating mutations (oncogenes) or …