[HTML][HTML] Global emerging Omicron variant of SARS-CoV-2: Impacts, challenges and strategies

K Dhama, F Nainu, A Frediansyah, MI Yatoo… - Journal of infection and …, 2023 - Elsevier
Newly emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
are continuously posing high global public health concerns and panic resulting in waves of …

Therapeutics for COVID-19

SS Toussi, JL Hammond, BS Gerstenberger… - Nature …, 2023 - nature.com
Vaccines and monoclonal antibody treatments to prevent severe coronavirus disease 2019
(COVID-19) illness were available within a year of the pandemic being declared but there …

Bivalent omicron BA. 1–adapted BNT162b2 booster in adults older than 55 years

P Winokur, J Gayed, D Fitz-Patrick… - … England Journal of …, 2023 - Mass Medical Soc
Background The emergence of immune-escape variants of severe acute respiratory
syndrome coronavirus 2 warrants the use of sequence-adapted vaccines to provide …

Clinical outcomes associated with SARS-CoV-2 Omicron (B. 1.1. 529) variant and BA. 1/BA. 1.1 or BA. 2 subvariant infection in Southern California

JA Lewnard, VX Hong, MM Patel, R Kahn, M Lipsitch… - Nature medicine, 2022 - nature.com
Epidemiologic surveillance has revealed decoupling of Coronavirus Disease 2019 (COVID-
19) hospitalizations and deaths from case counts after emergence of the Omicron (B. 1.1 …

Effectiveness of COVID-19 vaccines against Omicron and Delta hospitalisation, a test negative case-control study

J Stowe, N Andrews, F Kirsebom, M Ramsay… - Nature …, 2022 - nature.com
The Omicron variant has been associated with reduced vaccine effectiveness (VE) against
mild disease with rapid waning. Meanwhile Omicron has also been associated with milder …

Effectiveness of mRNA-1273 vaccination against SARS-CoV-2 omicron subvariants BA. 1, BA. 2, BA. 2.12. 1, BA. 4, and BA. 5

HF Tseng, BK Ackerson, KJ Bruxvoort, LS Sy… - Nature …, 2023 - nature.com
Studies have reported reduced natural SARS-CoV-2 infection-and vaccine-induced
neutralization against omicron BA. 4/BA. 5 compared with earlier omicron subvariants. This …

Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis

D Cromer, M Steain, A Reynaldi, TE Schlub… - Nature …, 2023 - nature.com
Vaccine protection from symptomatic SARS-CoV-2 infection has been shown to be strongly
correlated with neutralising antibody titres; however, this has not yet been demonstrated for …

Shedding of infectious SARS-CoV-2 despite vaccination

KK Riemersma, LA Haddock III, NA Wilson… - PLoS …, 2022 - journals.plos.org
The SARS-CoV-2 Delta Variant of Concern is highly transmissible and contains mutations
that confer partial immune escape. The emergence of Delta in North America caused the first …

Clinical outcomes among patients infected with Omicron (B. 1.1. 529) SARS-CoV-2 variant in southern California

JA Lewnard, VX Hong, MM Patel, R Kahn, M Lipsitch… - MedRxiv, 2022 - medrxiv.org
ABSTRACT Background The Omicron (B. 1.1. 529) variant of SARS-CoV-2 has rapidly
achieved global dissemination, accounting for most infections in the United States by …

Evolution of antibody immunity following Omicron BA. 1 breakthrough infection

CI Kaku, TN Starr, P Zhou, HL Dugan, P Khalifé… - Nature …, 2023 - nature.com
Understanding the longitudinal dynamics of antibody immunity following heterologous SAR-
CoV-2 breakthrough infection will inform the development of next-generation vaccines …