Lipid phosphoinositides are master regulators of almost all aspects of a cell's life and death
and are generated by the tightly regulated activity of phosphoinositide kinases. Although …

Lipid phosphoinositides are master regulators of multiple cellular functions. Misregulation of
the activity of the lipid kinases that generate phosphoinositides is causative of human …

Summary Apolipoproteins L1 and L3 (APOLs) are associated at the Golgi with the
membrane fission factors phosphatidylinositol 4-kinase-IIIB (PI4KB) and non-muscular …

The type III Phosphatidylinositol 4-kinase alpha (PI4KA) is an essential lipid kinase that is a
master regulator of phosphoinositide signalling at the plasma membrane (PM). It produces …

Abstract The Ser/Thr kinase protein kinase-D1 (PKD1) is involved in induction of various cell
physiological processes in the heart such as myocellular hypertrophy and inflammation …

Abstract Phosphatidylinositol 4-kinases (PI4Ks) could phosphorylate phosphatidylinositol
(PI) to produce phosphatidylinositol 4-phosphate (PI4P) and maintain its metabolic balance …

Phosphatidylinositol 4-monophosphate (PtdIns (4) P) is one of the key membrane
components which mark the membrane contact sites. In the mammalian Golgi complex …

A large amount of the human proteome is composed of highly dynamic regions that do not
adopt a single static conformation. These regions are defined as intrinsically disordered, and …

Rhinoviruses (RVs) are major instigators of acute exacerbations of asthma, COPD, and
other respiratory diseases. RVs are categorized into three species (RV-A, RV-B, and RV-C) …

In a recently published paper titled “ARMH3-mediated recruitment of PI4KB directs Golgi-to-
endosome trafficking and activation of the antiviral effector STING” published in Immunity …