Simple Summary This review depicts the principal mechanisms involved in the process of
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …

In tumor engineering, 3D approaches are used to model components of the tumor
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …

Background Although a substantial increase in the survival of patients with other cancers
has been observed in recent decades, pancreatic ductal adenocarcinoma (PDAC) remains …

Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide and is
predicted to become second in 2030 in industrialized countries if no therapeutic progress is …

Metastasis and tumor progression are the major cause of death in patients suffering from
pancreatic ductal adenocarcinoma. Tumor growth and especially dissemination are typically …

Pancreatic ductal adenocarcinoma (PDAC) has one of the worst outcomes among cancers
with a 5-years survival rate of below 10%. This is a result of late diagnosis and the lack of …

Aberrant expression of laminin-332 promotes tumour growth and metastasis in multiple
cancers. However, the dysregulated expression and mechanism of action of LAMB3, which …

Background Pancreatic cancer (PC) is a malignancy with a poor prognosis and high
mortality. Surgical resection is the only “curative” treatment. However, only a minority of …

The mechanism and gene markers of head and neck squamous cell carcinoma (HNSCC), a
common malignant tumor, have not yet been identified. The aim of this study was to identify …

Hepatocellular carcinoma (HCC) is one of the primary causes of cancer‑associated deaths
worldwide. Current treatment methods include surgical resection, chemotherapy and …