The tumor microenvironment: a key player in multidrug resistance in cancer
L Meng, Y Zheng, H Liu, D Fan - Oncologie, 2024 - degruyter.com
Cancer is the second leading cause of death worldwide. Although multiple new cancer
treatments have emerged in recent years, drug therapy, mainly comprising chemotherapy …
treatments have emerged in recent years, drug therapy, mainly comprising chemotherapy …
Recent advances in understanding the immune microenvironment in ovarian cancer
J Chen, L Yang, Y Ma, Y Zhang - Frontiers in Immunology, 2024 - frontiersin.org
The occurrence of ovarian cancer (OC) is a major factor in women's mortality rates. Despite
progress in medical treatments, like new drugs targeting homologous recombination …
progress in medical treatments, like new drugs targeting homologous recombination …
[HTML][HTML] Analysis and experimental validation of fatty acid metabolism-related genes prostacyclin synthase (PTGIS) in endometrial cancer
B Wang, S Ge, Z Wang, W Wang, Y Wang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
The deregulation of fatty acid metabolism plays a pivotal role in cancer. Our objective is to
construct a prognostic model for patients with endometrial carcinoma (EC) based on genes …
construct a prognostic model for patients with endometrial carcinoma (EC) based on genes …
Identification and experimental validation of Stearoyl-CoA desaturase is a new drug therapeutic target for osteosarcoma
J Nie, C He, Z Shu, N Liu, Y Zhong, X Long, J Liu… - European Journal of …, 2024 - Elsevier
Osteosarcoma (OS) is the most common malignant bone tumor. Fatty acid reprogramming
plays an essential role in OS progression. However, new fatty acid related therapeutic …
plays an essential role in OS progression. However, new fatty acid related therapeutic …
Comprehensive investigation of malignant epithelial cell-related genes in clear cell renal cell carcinoma: development of a prognostic signature and exploration of …
S Liu, G Li, X Yin, Y Zhou, D Luo, Z Yang… - Journal of Translational …, 2024 - Springer
Clear cell renal cell carcinoma (ccRCC) is a prevalent malignancy with complex
heterogeneity within epithelial cells, which plays a crucial role in tumor progression and …
heterogeneity within epithelial cells, which plays a crucial role in tumor progression and …
The role of tumor-associated macrophages in tumor immune evasion
R Huang, T Kang, S Chen - Journal of Cancer Research and Clinical …, 2024 - Springer
Background Tumor growth is closely linked to the activities of various cells in the tumor
microenvironment (TME), particularly immune cells. During tumor progression, circulating …
microenvironment (TME), particularly immune cells. During tumor progression, circulating …
M2 macrophages promote PD-L1 expression in triple-negative breast cancer via secreting CXCL1
L Zhang, S Gu, L Wang, L Zhao, T Li, X Zhao… - … -Research and Practice, 2024 - Elsevier
Background M2 macrophages are known to play a significant role in the progression of triple-
negative breast cancer (TNBC) by creating an immunosuppressive microenvironment. The …
negative breast cancer (TNBC) by creating an immunosuppressive microenvironment. The …
Фенотипические и транскриптомные особенности моноцитов периферической крови в динамике неоадъювантной химиотерапии больных раком молочной …
МР Патышева, МН Стахеева… - Успехи …, 2024 - umo.abvpress.ru
Аннотация Введение. Химиотерапия включена в большинство схем лечения рака
молочной железы. Действие химиотерапевтических препаратов оказывает влияние на …
молочной железы. Действие химиотерапевтических препаратов оказывает влияние на …
The relationship between the metabolic enzyme hexokinase 2 and cancer immunity: a pan-cancer analysis
LX Li, X Gao - 2023 - researchsquare.com
Background: Hexokinase 2 (HK2) takes on critical significance in glycolysis as the primary
rate-limiting enzyme, which can carefully control the phosphorylation of glucose. The non …
rate-limiting enzyme, which can carefully control the phosphorylation of glucose. The non …
Increased Infiltration of M2-Polarized Tumour-Associated Macrophages is Highly Associated with Advanced Disease Stage and High Expression of PD-L1 in Buccal …
HJ Sun, ZF Zheng, LJ Zhang, L Fang, H Fu, SY Chen… - 2023 - researchsquare.com
Objective: To assess the infiltration characteristics of tumour-associated macrophages
(TAMs) in buccal mucosa carcinoma (BMC) and the correlation of these features with …
(TAMs) in buccal mucosa carcinoma (BMC) and the correlation of these features with …